HitPredict

Interactor 1: ACTN4 (O43707)
Alpha-actinin-4 (Non-muscle alpha-actinin 4)
Gene: ACTN4

Interactor 2: CAZA2 (P47755)
F-actin-capping protein subunit alpha-2 (CapZ alpha-2)
Gene: CAPZA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26496610, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0015629 - actin cytoskeleton GO:0030036 - actin cytoskeleton organization GO:0051015 - actin filament binding GO:0070062 - extracellular exosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 911 Hs			1 286
+	Hs
		521495 ACTN1_HUMAN (20-911): 0: 607: 85.76		CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00
+	Hs
		211540 ACTN4_HUMAN (1-911): 0: 586: 100.00		CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71
+	Hs
		812991 SPTB2_HUMAN (215-825): 5.91e-11: 68.9: 10.75		CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00
+	Hs
		164581 SPTN2_HUMAN (262-846): 1.08e-09: 64.7: 12.62		CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00