HitPredict

Interactor 1: SPIT2 (O43291)
Kunitz-type protease inhibitor 2 (Hepatocyte growth factor activator inhibitor type 2) (HAI-2) (Placental bikunin)
Gene: SPINT2

Interactor 2: S39AA (Q9ULF5)
Zinc transporter ZIP10 (Solute carrier family 39 member 10) (Zrt- and Irt-like protein 10) (ZIP-10)
Gene: SLC39A10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 252 Hs			1 831
+	Hs
		1055375 APLP2_HUMAN (22-132): 1.07e-25: 107: 20.72		S39AA_HUMAN (1-831): 0: 939: 100.00
+	Hs
		423438 A4_HUMAN (136-185): 4.8e-20: 91: 54.00		S39AA_HUMAN (1-831): 0: 939: 100.00
+	Hs
		212396 SPIT2_HUMAN (1-252): 7.91e-92: 272: 100.00		S39A6_HUMAN (311-831): 4.68e-128: 403: 43.85
+	Hs
		212477 SPIT2_HUMAN (1-252): 7.91e-92: 272: 100.00		S39A3_HUMAN (495-818): 3.35e-48: 175: 11.28
+	Hs
		1055319 APLP2_HUMAN (22-132): 1.07e-25: 107: 20.72		S39AC_HUMAN (335-825): 7.46e-67: 237: 24.49
+	Hs
		1055323 APLP2_HUMAN (22-132): 1.07e-25: 107: 20.72		S39A4_HUMAN (337-827): 2.63e-62: 223: 21.95
+	Hs
		422241 A4_HUMAN (136-185): 4.8e-20: 91: 54.00		S39AC_HUMAN (335-825): 7.46e-67: 237: 24.49
+	Hs
		422746 A4_HUMAN (136-185): 4.8e-20: 91: 54.00		S39A7_HUMAN (462-810): 4.54e-64: 224: 22.79
+	Hs
		423322 A4_HUMAN (136-185): 4.8e-20: 91: 54.00		S39A1_HUMAN (512-818): 5.37e-49: 178: 14.79