HitPredict

Interactor 1: DAPK3 (O43293)
Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)
Gene: DAPK3

Interactor 2: LUZP1 (Q86V48)
Leucine zipper protein 1 (Filamin mechanobinding actin cross-linking protein) (Fimbacin)
Gene: LUZP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.671

Property	Details
Experiments	33961781, 35271311, 32707033
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000775 - chromosome, centromeric region GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0030496 - midbody
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 1076
+	Hs
		212677 DAPK3_HUMAN (1-454): 1.18e-158: 458: 100.00		MY18A_HUMAN (72-652): 1.93e-31: 136: 12.91
+	Hs
		156718 DAPK3_HUMAN (1-454): 1.18e-158: 458: 100.00		CTRO_HUMAN (27-558): 1.53e-24: 113: 12.04
+	Hs
		212690 DAPK3_HUMAN (1-454): 1.18e-158: 458: 100.00		MYO5C_HUMAN (1-378): 1.74e-18: 93.7: 11.63
+	Hs
		212670 DAPK3_HUMAN (1-454): 1.18e-158: 458: 100.00		FLIP1_HUMAN (76-616): 1.65e-13: 77.5: 12.84
+	Hs
		212639 DAPK3_HUMAN (1-454): 1.18e-158: 458: 100.00		MYH9_HUMAN (1-353): 3.2e-12: 73.3: 13.65
+	Hs
		157961 DAPK2_HUMAN (1-296): 7.51e-134: 391: 74.26		CTRO_HUMAN (27-558): 1.53e-24: 113: 12.04
+	Hs
		772822 MYLK_HUMAN (6-308): 2.39e-74: 256: 43.09		MYH9_HUMAN (1-353): 3.2e-12: 73.3: 13.65
+	Rn
		236529 KALRN_RAT (6-276): 3.83e-62: 220: 40.59		MRCKA_RAT (226-673): 4.5e-23: 108: 10.11
+	Mm
		60078 KALRN_MOUSE (6-276): 3.76e-62: 220: 40.59		CTRO_MOUSE (163-645): 3.64e-22: 105: 9.52
+	Rn
		1022058 KALRN_RAT (6-276): 3.83e-62: 220: 40.59		MRCKB_RAT (255-644): 1.55e-20: 100: 10.70