Interactor 1: RIPK2 (O43353)
Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2)
Gene: RIPK2
Interactor 2: BIRC3 (Q13489)
Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1)
Gene: BIRC3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.83 | 1.00 | 0.916 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CARD~CARD, CARD~zf-C3HC4_3, BIR~PK_Tyr_Ser-Thr |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006915 - apoptotic process GO:0007249 - canonical NF-kappaB signal transduction GO:0031398 - positive regulation of protein ubiquitination and 2 others more... |
| Homologous interactions | 17 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
