Protein: SC6A8
Sodium- and chloride-dependent creatine transporter 1 (CT1) (Creatine transporter 1) (Solute carrier family 6 member 8)

Gene: SC6A8, SLC6A8
Organism: Homo sapiens
Interactions: 138
UniProt ID: P48029

Gene Ontology (top 5):
GO:0005308 - creatine transmembrane transporter activity
GO:0005309 - creatine:sodium symporter activity
GO:0005332 - gamma-aminobutyric acid:sodium:chloride symporter activity
GO:0005886 - plasma membrane
GO:0006600 - creatine metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

674833

AGTR1
Type-1 angiotensin II receptor

3

4

High-throughput

0.667

High

599780

5NTD
5'-nucleotidase

3

0

High-throughput

0.638

High

674781

GRPR
Gastrin-releasing peptide receptor

2

2

High-throughput

0.628

High

815815

YIPF3
Protein YIPF3

2

1

High-throughput

0.628

High

793232

MUC18
Cell surface glycoprotein MUC18

1

3

High-throughput

0.618

High

815767

CXAR
Coxsackievirus and adenovirus receptor

1

3

High-throughput

0.618

High

654152

CALX
Calnexin

2

5

Small-scale

0.611

High

793173

PI2R
Prostacyclin receptor

2

0

High-throughput

0.602

High

815792

TPRA1
Transmembrane protein adipocyte-associated 1

2

0

High-throughput

0.602

High

205158

TGON2
Trans-Golgi network integral membrane protein 2

2

3

High-throughput

0.584

High

305383

ZFPL1
Zinc finger protein-like 1

2

1

Small-scale

0.584

High

348565

RASN
GTPase NRas

2

19

High-throughput

0.584

High

349966

RASK
GTPase KRas

2

19

High-throughput

0.584

High

815757

SC61B
Protein transport protein Sec61 subunit beta

2

1

High-throughput

0.584

High

815765

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.584

High

445773

ACM5
Muscarinic acetylcholine receptor M5

1

3

High-throughput

0.541

High

804963

BKRB1
B1 bradykinin receptor

1

2

High-throughput

0.541

High

155890

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

1

High-throughput

0.536

High

318469

CDS2
Phosphatidate cytidylyltransferase 2

1

1

High-throughput

0.536

High

598926

FPR1
fMet-Leu-Phe receptor

1

4

High-throughput

0.536

High

600747

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

3

High-throughput

0.536

High

626504

FPR2
N-formyl peptide receptor 2

1

4

High-throughput

0.536

High

677582

NTR1
Neurotensin receptor type 1

1

1

High-throughput

0.536

High

814238

GLR
Glucagon receptor

1

1

High-throughput

0.536

High

815773

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

1

High-throughput

0.536

High

815789

TLCD5
TLC domain-containing protein 5

1

1

High-throughput

0.536

High

50108

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.513

High

179310

COPT2
Protein SLC31A2

1

0

High-throughput

0.513

High

815749

PTSS1
Phosphatidylserine synthase 1

1

0

High-throughput

0.513

High

815805

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

0

High-throughput

0.513

High

815813

S26A6
Solute carrier family 26 member 6

1

0

High-throughput

0.513

High

815816

S22A4
Solute carrier family 22 member 4

1

0

High-throughput

0.513

High

815826

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.513

High

120342

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

170814

PGRC2
Membrane-associated progesterone receptor component 2

1

2

Small-scale

0.479

High

178429

STX7
Syntaxin-7

1

15

High-throughput

0.479

High

212758

STX6
Syntaxin-6

1

4

High-throughput

0.479

High

279479

FLOT1
Flotillin-1

1

3

High-throughput

0.479

High

318082

DIRA3
GTP-binding protein Di-Ras3

1

9

High-throughput

0.479

High

326858

FADS2
Acyl-CoA 6-desaturase

1

3

Small-scale

0.479

High

390113

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.479

High

390764

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.479

High

433643

LYN
Tyrosine-protein kinase Lyn

1

4

High-throughput

0.479

High

436200

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

506919

LAMP1
Lysosome-associated membrane glycoprotein 1

1

7

High-throughput

0.479

High

527341

LAMP2
Lysosome-associated membrane glycoprotein 2

1

7

High-throughput

0.479

High

545257

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

546974

EZRI
Ezrin

1

5

High-throughput

0.479

High

560169

NCPR
NADPH--cytochrome P450 reductase

1

2

Small-scale

0.479

High

564450

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

566965

CXA1
Gap junction alpha-1 protein

1

4

High-throughput

0.479

High

572315

LEG3
Galectin-3

1

1

Small-scale

0.479

High

591521

RAB3B
Ras-related protein Rab-3B

1

4

High-throughput

0.479

High

591767

RAB4A
Ras-related protein Rab-4A

1

8

High-throughput

0.479

High

592152

RAB5A
Ras-related protein Rab-5A

1

8

High-throughput

0.479

High

669922

MARCS
Myristoylated alanine-rich C-kinase substrate

1

3

High-throughput

0.479

High

729244

VGFR3
Vascular endothelial growth factor receptor 3

1

5

High-throughput

0.479

High

815750

LMAN1
Protein ERGIC-53

1

1

High-throughput

0.479

High

815751

RAB5C
Ras-related protein Rab-5C

1

8

High-throughput

0.479

High

815752

RAB9A
Ras-related protein Rab-9A

1

8

High-throughput

0.479

High

815753

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.479

High

815755

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

815756

AFAD
Afadin

1

14

High-throughput

0.479

High

815758

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

815759

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

815761

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

815762

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

815763

ARF6
ADP-ribosylation factor 6

1

3

High-throughput

0.479

High

815766

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

815768

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

815769

CAV1
Caveolin-1

1

1

High-throughput

0.479

High

815770

KDSR
3-ketodihydrosphingosine reductase

1

4

Small-scale

0.479

High

815771

CKAP4
Cytoskeleton-associated protein 4

1

3

High-throughput

0.479

High

815772

STX4
Syntaxin-4

1

15

High-throughput

0.479

High

815776

RAB35
Ras-related protein Rab-35

1

5

High-throughput

0.479

High

815778

TRAM1
Translocating chain-associated membrane protein 1

1

1

Small-scale

0.479

High

815779

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

815780

OCLN
Occludin

1

1

High-throughput

0.479

High

815784

S27A3
Long-chain fatty acid transport protein 3

1

3

Small-scale

0.479

High

815786

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

815791

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

815795

CXD3
Gap junction delta-3 protein

1

4

High-throughput

0.479

High

815797

T161B
Transmembrane protein 161B

1

1

Small-scale

0.479

High

815798

LMBR1
Limb region 1 protein homolog

1

1

Small-scale

0.479

High

815800

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.479

High

815801

CDS1
Phosphatidate cytidylyltransferase 1

1

1

Small-scale

0.479

High

815802

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

2

High-throughput

0.479

High

815806

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.479

High

815809

SEC62
Translocation protein SEC62

1

1

High-throughput

0.479

High

815811

CHP1
Calcineurin B homologous protein 1

1

2

Small-scale

0.479

High

815819

DNJC5
DnaJ homolog subfamily C member 5

1

5

High-throughput

0.479

High

815820

FZD8
Frizzled-8

1

1

Small-scale

0.479

High

815821

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

815822

TMT1A
Thiol S-methyltransferase TMT1A

1

1

High-throughput

0.479

High

815823

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

815827

T161A
Transmembrane protein 161A

1

1

Small-scale

0.479

High

815828

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.479

High

815829

TM216
Transmembrane protein 216

1

3

High-throughput

0.479

High

815830

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

2

High-throughput

0.479

High

815831

DNJ5B
DnaJ homolog subfamily C member 5B

1

5

High-throughput

0.479

High

815834

LAMP3
Lysosome-associated membrane glycoprotein 3

1

7

High-throughput

0.479

High

568582

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

0

High-throughput

0.458

High

815774

S39A6
Zinc transporter ZIP6

1

0

Small-scale

0.458

High

815785

LMBD2
G-protein coupled receptor-associated protein LMBRD2

1

0

Small-scale

0.458

High

815788

QSOX2
Sulfhydryl oxidase 2

1

0

Small-scale

0.458

High

815807

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

815808

PIGS
GPI transamidase component PIG-S

1

0

Small-scale

0.458

High

815810

SORT
Sortilin

1

0

Small-scale

0.458

High

815812

G6PC3
Glucose-6-phosphatase 3

1

0

Small-scale

0.458

High

815814

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

Small-scale

0.458

High

815824

SEC12
Guanine nucleotide-exchange factor SEC12

1

0

Small-scale

0.458

High

815832

MA1B1
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

1

0

Small-scale

0.458

High

815835

UBIA1
UbiA prenyltransferase domain-containing protein 1

1

0

Small-scale

0.458

High

815836

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

0

Small-scale

0.458

High

132430

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

156473

SCAM3
Secretory carrier-associated membrane protein 3

1

2

Small-scale

0.437

High

161038

CLGN
Calmegin

1

5

Small-scale

0.437

High

486488

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

1

High-throughput

0.437

High

815760

RAB2A
Ras-related protein Rab-2A

1

8

High-throughput

0.437

High

815764

RB11A
Ras-related protein Rab-11A

1

3

High-throughput

0.437

High

815777

KS6A2
Ribosomal protein S6 kinase alpha-2

1

2

High-throughput

0.437

High

815781

TM41B
Transmembrane protein 41B

1

2

High-throughput

0.437

High

815783

SYEM
Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial

1

1

Small-scale

0.437

High

815790

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

815793

TMM17
Transmembrane protein 17

1

3

High-throughput

0.437

High

815796

DHB11
Estradiol 17-beta-dehydrogenase 11

1

3

High-throughput

0.437

High

815799

SNX19
Sorting nexin-19

1

1

Small-scale

0.437

High

815803

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

815804

RFT1
Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1

1

1

Small-scale

0.437

High

815818

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

1

High-throughput

0.437

High

815754

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

0

Small-scale

0.249

Low

815775

OS9
Protein OS-9

1

0

Small-scale

0.249

Low

815782

MKS3
Meckelin

1

0

High-throughput

0.249

Low

815787

TECT3
Tectonic-3

1

0

High-throughput

0.249

Low

815794

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.249

Low

815817

UN93B
Protein unc-93 homolog B1

1

0

Small-scale

0.249

Low

815825

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

815833

EPDR1
Mammalian ependymin-related protein 1

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024