Interactor 1: FRS3 (O43559)
Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FGFR-signaling adaptor SNT2) (Suc1-associated neurotrophic factor target 2) (SNT-2)
Gene: FRS3
Interactor 2: FRS3 (O43559)
Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FGFR-signaling adaptor SNT2) (Suc1-associated neurotrophic factor target 2) (SNT-2)
Gene: FRS3
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.81 | 1.00 | 0.901 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25814554, 32296183, unassigned1126, unassigned1304 |
| Identification Methods | two hybrid, affinity chromatography technology, two hybrid array, luminescence based mammalian interactome mapping, validated two hybrid, two hybrid prey pooling approach |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | IRS~IRS |
| Common GO terms | GO:0005068 - transmembrane receptor protein tyrosine kinase adaptor activity GO:0005104 - fibroblast growth factor receptor binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0007165 - signal transduction and 1 others more... |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
