Protein: DOK3
Docking protein 3 (Downstream of tyrosine kinase 3)

Gene: DOK3
Organism: Homo sapiens
Interactions: 52
UniProt ID: Q7L591

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
GO:0007265 - Ras protein signal transduction
GO:0030667 - secretory granule membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1272285

DOK4
Docking protein 4

2

11

High-throughput

0.819

High

249762

DOK2
Docking protein 2

2

13

High-throughput

0.767

High

1272293

DOK1
Docking protein 1

2

11

High-throughput

0.767

High

1272301

DOK5
Docking protein 5

2

11

High-throughput

0.767

High

1272302

DP13A
DCC-interacting protein 13-alpha

2

4

High-throughput

0.767

High

1272283

DP13B
DCC-interacting protein 13-beta

2

4

High-throughput

0.743

High

1272298

PKHA3
Pleckstrin homology domain-containing family A member 3

2

2

High-throughput

0.700

High

1093858

TRAF1
TNF receptor-associated factor 1

4

3

High-throughput

0.698

High

709135

TPP2
Tripeptidyl-peptidase 2

4

1

High-throughput

0.691

High

1272300

MIOS
GATOR2 complex protein MIOS

4

1

High-throughput

0.691

High

1250388

DPP8
Dipeptidyl peptidase 8

3

1

High-throughput

0.667

High

246002

KIF1B
Kinesin-like protein KIF1B

1

2

High-throughput

0.665

High

1272297

WDR54
WD repeat-containing protein 54

3

0

High-throughput

0.638

High

1272280

DOK3
Docking protein 3

1

11

Small-scale

0.618

High

1272292

DC2I2
Cytoplasmic dynein 2 intermediate chain 2

2

1

High-throughput

0.611

High

1272287

SHC3
SHC-transforming protein 3

2

20

High-throughput

0.606

High

1272295

SPAG8
Sperm-associated antigen 8

2

1

High-throughput

0.606

High

1272299

A1CF
APOBEC1 complementation factor

2

2

High-throughput

0.606

High

827827

STAT3
Signal transducer and activator of transcription 3

2

2

High-throughput

0.594

High

855664

CRK
Adapter molecule crk

2

20

High-throughput

0.594

High

363484

EGFR
Epidermal growth factor receptor

1

20

Small-scale

0.582

High

216266

PPIH
Peptidyl-prolyl cis-trans isomerase H

2

0

High-throughput

0.580

High

225622

AAKB2
5'-AMP-activated protein kinase subunit beta-2

2

0

High-throughput

0.580

High

1272282

DTX2
Probable E3 ubiquitin-protein ligase DTX2

2

0

High-throughput

0.580

High

1272294

MDFI
MyoD family inhibitor

2

0

High-throughput

0.580

High

1272288

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

3

6

High-throughput

0.580

High

1224837

TENS2
Tensin-2

2

3

High-throughput

0.576

High

1272284

RIN3
Ras and Rab interactor 3

2

1

High-throughput

0.576

High

1272296

QTRT2
Queuine tRNA-ribosyltransferase accessory subunit 2

2

0

High-throughput

0.576

High

1272290

RBPMS
RNA-binding protein with multiple splicing

1

1

High-throughput

0.573

High

987733

GRB2
Growth factor receptor-bound protein 2

2

20

Small-scale

0.571

High

885311

HXA1
Homeobox protein Hox-A1

2

1

High-throughput

0.553

High

1219570

SHE
SH2 domain-containing adapter protein E

2

20

High-throughput

0.542

High

537402

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.536

High

930958

HSP72
Heat shock-related 70 kDa protein 2

1

3

High-throughput

0.536

High

1272286

BLNK
B-cell linker protein

1

18

Small-scale

0.536

High

415673

HSPB1
Heat shock protein beta-1

1

2

High-throughput

0.515

High

1193611

Q49AR9
ANKS1A protein

1

10

High-throughput

0.515

High

651371

CBL
E3 ubiquitin-protein ligase CBL

1

6

Small-scale

0.479

High

971702

1433E
14-3-3 protein epsilon

1

5

Small-scale

0.479

High

1182838

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

1

2

High-throughput

0.479

High

1272289

SHIP1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

1

7

Small-scale

0.479

High

1272303

RNF11
RING finger protein 11

1

1

High-throughput

0.470

High

1272281

DPP9
Dipeptidyl peptidase 9

1

1

High-throughput

0.437

High

1272291

COA7
Cytochrome c oxidase assembly factor 7

1

1

High-throughput

0.407

High

49113

BLT3B
Bridge-like lipid transfer protein family member 3B

3

0

High-throughput

0.347

High

607700

DCAM
S-adenosylmethionine decarboxylase proenzyme

3

0

High-throughput

0.347

High

288307

GCM2
Chorion-specific transcription factor GCMb

2

0

High-throughput

0.316

High

528467

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

2

0

High-throughput

0.316

High

521775

H14
Histone H1.4

1

0

High-throughput

0.269

Low

301512

WFS1
Wolframin

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025