Protein: DOK2
Docking protein 2 (Dok-related protein) (Dok-R) (Downstream of tyrosine kinase 2) (IL-four receptor-interacting protein) (FRIP) (p56(dok-2))

Gene: DOK2
Organism: Mus musculus
Interactions: 13
UniProt ID: O70469

Gene Ontology (top 5):
GO:0005068 - transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005886 - plasma membrane
GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
GO:0007265 - Ras protein signal transduction
GO:0043409 - negative regulation of MAPK cascade

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

97773

E9PYG6
Ras GTPase-activating protein 1

3

20

Small-scale

0.827

High

267121

Q91YX7
Ras GTPase-activating protein 1

2

20

Small-scale

0.759

High

237067

NCK2
Cytoplasmic protein NCK2

2

20

Small-scale

0.705

High

267117

DOK1
Docking protein 1

1

11

High-throughput

0.691

High

267122

NCK1
SH2/SH3 adapter protein Nck1

1

20

High-throughput

0.691

High

267114

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.690

High

267116

CSK
Tyrosine-protein kinase CSK

1

20

Small-scale

0.665

High

267118

EGFR
Epidermal growth factor receptor

1

20

Small-scale

0.618

High

267119

BCR
Breakpoint cluster region protein

1

2

High-throughput

0.618

High

267113

ABL1
Tyrosine-protein kinase ABL1

1

20

Small-scale

0.595

High

267123

SHIP1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

1

7

High-throughput

0.536

High

267115

LYN
Tyrosine-protein kinase Lyn

1

20

Small-scale

0.436

High

267120

BICD1
Protein bicaudal D homolog 1

1

1

High-throughput

0.407

High


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Last updated: 11Aug2025