HitPredict

Interactor 1: NCK2 (O43639)
Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
Gene: NCK2

Interactor 2: SHRM2 (Q13796)
Protein Shroom2 (Apical-like protein) (Protein APXL)
Gene: SHROOM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007015 - actin filament organization GO:0016477 - cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 380 Hs			1 1616
+	Hs
		593988 NCK1_HUMAN (1-379): 3.58e-88: 272: 68.24		SHRM2_HUMAN (1-1616): 8.59e-175: 571: 100.00
+	Hs
		440546 FYN_HUMAN (7-140): 3.47e-22: 99.9: 19.85		SHRM2_HUMAN (1-1616): 8.59e-175: 571: 100.00
+	Hs
		557289 SRC_HUMAN (6-155): 4.28e-19: 90.6: 17.11		SHRM2_HUMAN (1-1616): 8.59e-175: 571: 100.00
+	Hs
		319045 LYN_HUMAN (2-205): 8.56e-23: 101: 14.56		K0754_HUMAN (797-1606): 3.06e-63: 241: 14.42
+	Hs
		1040391 ITSN2_HUMAN (5-273): 6.53e-36: 141: 19.27		DYST_HUMAN (1316-1609): 5.43e-49: 195: 13.61
+	Hs
		1040304 ITSN1_HUMAN (5-253): 2.96e-28: 119: 16.61		DYST_HUMAN (1316-1609): 5.43e-49: 195: 13.61
+	Hs
		463316 LYN_HUMAN (2-205): 8.56e-23: 101: 14.56		MUC1_HUMAN (431-1443): 2.05e-53: 208: 8.98
+	Hs
		439935 LCK_HUMAN (3-205): 1.6e-19: 91.8: 16.59		MUC1_HUMAN (431-1443): 2.05e-53: 208: 8.98
+	Hs
		557066 SRC_HUMAN (6-155): 4.28e-19: 90.6: 17.11		MUC1_HUMAN (431-1443): 2.05e-53: 208: 8.98
+	Hs
		463467 LYN_HUMAN (2-205): 8.56e-23: 101: 14.56		DYST_HUMAN (1316-1609): 5.43e-49: 195: 13.61
+	Hs
		590268 GRB2_HUMAN (3-60): 5.23e-18: 84: 29.31		MUC1_HUMAN (431-1443): 2.05e-53: 208: 8.98
+	Hs
		440036 LCK_HUMAN (3-205): 1.6e-19: 91.8: 16.59		DYST_HUMAN (1316-1609): 5.43e-49: 195: 13.61
+	Hs
		463842 LYN_HUMAN (2-205): 8.56e-23: 101: 14.56		MACF1_HUMAN (1440-1606): 4.42e-45: 182: 17.44
+	Hs
		987557 GRB2_HUMAN (3-60): 5.23e-18: 84: 29.31		DYST_HUMAN (1316-1609): 5.43e-49: 195: 13.61
+	Hs
		440243 LCK_HUMAN (3-205): 1.6e-19: 91.8: 16.59		MACF1_HUMAN (1440-1606): 4.42e-45: 182: 17.44
+	Hs
		270702 SRC_HUMAN (6-155): 4.28e-19: 90.6: 17.11		LDB3_HUMAN (27-557): 4.1e-30: 131: 14.88
+	Hs
		440773 FYN_HUMAN (7-140): 3.47e-22: 99.9: 19.85		MAGL2_HUMAN (885-1469): 2.18e-19: 97.5: 10.05
+	Hs
		117131 J3QRU1_HUMAN (6-137): 1.8e-19: 92.1: 20.15		PDLI7_HUMAN (29-245): 1.5e-16: 86.3: 21.88
+	Hs
		463235 YES_HUMAN (6-137): 1.81e-19: 91.7: 20.15		PDLI7_HUMAN (29-245): 1.5e-16: 86.3: 21.88
+	Hs
		440219 LCK_HUMAN (3-205): 1.6e-19: 91.8: 16.59		NCK5L_HUMAN (109-1137): 8.71e-13: 75.9: 9.52