HitPredict

Interactor 1: TRA2A (Q13595)
Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)
Gene: TRA2A

Interactor 2: YTDC1 (Q96MU7)
YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B)
Gene: YTHDC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.695

Property	Details
Experiments	26186194, 28514442, 33961781, 21988832
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 282 Hs			1 727
+	Hs
		925106 TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30		YTDC1_HUMAN (1-673): 0: 567: 100.00
+	Hs
		201704 MSI1H_HUMAN (100-255): 8.46e-26: 106: 22.22		YTDC1_HUMAN (1-673): 0: 567: 100.00
+	Zm
		28088 O48554_MAIZE (122-195): 4.12e-26: 101: 41.89		A0A1D6JP38_MAIZE (264-551): 6.21e-107: 346: 21.36
+	Hs
		1031506 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		YTHD2_HUMAN (300-520): 2.5e-88: 290: 23.71
+	Hs
		516767 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		YTHD2_HUMAN (300-520): 2.5e-88: 290: 23.71
+	Hs
		1031376 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		YTHD3_HUMAN (300-503): 4.24e-83: 276: 22.48
+	Hs
		516575 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		YTHD3_HUMAN (300-503): 4.24e-83: 276: 22.48
+	Hs
		1031449 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		YTHD1_HUMAN (300-521): 7.77e-81: 270: 22.55
+	Hs
		516679 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		YTHD1_HUMAN (300-521): 7.77e-81: 270: 22.55
+	Hs
		963542 TIAR_HUMAN (113-209): 9.67e-20: 89.4: 20.62		YTHD3_HUMAN (300-503): 4.24e-83: 276: 22.48