Interactor 1: PTEN (O54857)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Inositol polyphosphate 3-phosphatase) (EC 3.1.3.-) (Phosphatase and tensin homolog)
Gene: PTEN
Interactor 2: CSK (P32577)
Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase)
Gene: CSK
Species: Rattus norvegicus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27391443 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PK_Tyr_Ser-Thr~Y_phosphatase, SH2~Y_phosphatase |
| Common GO terms | GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0008285 - negative regulation of cell population proliferation GO:1990782 - protein tyrosine kinase binding |
| Homologous interactions | 8 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
