Interactor 1: PTEN (O54857)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Inositol polyphosphate 3-phosphatase) (EC 3.1.3.-) (Phosphatase and tensin homolog)
Gene: PTEN

Interactor 2: NEDD4 (Q62940)
E3 ubiquitin-protein ligase NEDD4 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase NEDD4)
Gene: NEDD4

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 33712741, 20100827
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0019899 - enzyme binding
and 4 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 403
Rn

1 887
+ Hs
+ Hs
+ Mm
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Sc
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024