Interactor 1: PER2 (O54943)
Period circadian protein homolog 2 (mPER2) (Circadian clock protein PERIOD 2)
Gene: PER2

Interactor 2: CRY2 (Q9R194)
Cryptochrome-2
Gene: CRY2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.965

The method score is based on:

Property Details
Experiments 14701732, 26903623, 25127877, 23503662, 24737000, 22170608, 23555304, 20840750, 23079727
Identification Methods affinity chromatography technology, x-ray crystallography, anti tag coimmunoprecipitation, two hybrid, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_photolyase~Period_C, FAD_binding_7~Period_C
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 9 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1257
Mm

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Last updated: 15 Jul 2024