Interactor 1: LAT (O54957)
Linker for activation of T-cells family member 1 (36 kDa phosphotyrosine adapter protein) (pp36) (p36-38)
Gene: LAT

Interactor 2: ITK (Q03526)
Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) (T-cell-specific kinase)
Gene: ITK

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 24584089
Identification Methods affinity chromatography technology
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002250 - adaptive immune response
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0035556 - intracellular signal transduction
GO:0050852 - T cell receptor signaling pathway
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 242
Mm

1 625
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024