HitPredict

Interactor 1: TCF21 (O43680)
Transcription factor 21 (TCF-21) (Capsulin) (Class A basic helix-loop-helix protein 23) (bHLHa23) (Epicardin) (Podocyte-expressed 1) (Pod-1)
Gene: TCF21

Interactor 2: LMO4 (P61968)
LIM domain transcription factor LMO4 (Breast tumor autoantigen) (LIM domain only protein 4) (LMO-4)
Gene: LMO4

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	15231748
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	HLH~LIM
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005667 - transcription regulator complex GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 179 Hs			1 165
+	Mm
		644244 TAL1_MOUSE (42-177): 4.36e-30: 113: 31.94		RBTN2_MOUSE (23-148): 4e-46: 149: 45.67
+	Hs
		581779 MYOG_HUMAN (6-179): 1.85e-32: 117: 16.95		LMO3_HUMAN (13-152): 6.28e-41: 136: 47.86
+	Mm
		644382 TAL1_MOUSE (42-177): 4.36e-30: 113: 31.94		LMO3_MOUSE (13-152): 6.28e-41: 136: 47.86
+	Hs
		605169 TAL1_HUMAN (42-177): 2.16e-30: 114: 29.45		RBTN2_HUMAN (23-140): 7.71e-36: 123: 46.61
+	Hs
		605170 TAL1_HUMAN (42-177): 2.16e-30: 114: 29.45		RBTN1_HUMAN (1-143): 1.21e-35: 123: 48.25
+	Mm
		1223977 TAL2_MOUSE (80-179): 1.22e-25: 96.5: 31.37		LMO3_MOUSE (13-152): 6.28e-41: 136: 47.86
+	Hs
		681821 TAL2_HUMAN (80-166): 1.17e-26: 99.2: 31.03		RBTN2_HUMAN (23-140): 7.71e-36: 123: 46.61
+	Hs
		682035 TAL2_HUMAN (80-166): 1.17e-26: 99.2: 31.03		RBTN1_HUMAN (1-143): 1.21e-35: 123: 48.25
+	Mm
		1223978 TAL2_MOUSE (80-179): 1.22e-25: 96.5: 31.37		RBTN1_MOUSE (1-143): 2.5e-35: 122: 48.25
+	Hs
		681791 HEN1_HUMAN (81-136): 8.75e-23: 89.9: 46.43		RBTN2_HUMAN (23-140): 7.71e-36: 123: 46.61
+	Dm
		84289 DIMM_DROME (20-174): 1.25e-26: 105: 20.73		APTE_DROME (87-165): 1.84e-11: 63.1: 21.74
+	Dm
		1465666 Q9VHG3_DROME (12-164): 4.06e-27: 104: 20.25		Q9V472_DROME (14-92): 9.61e-12: 63.9: 25.00
+	Dm
		120449 Q9VHG3_DROME (12-164): 4.06e-27: 104: 20.25		M9PD53_DROME (12-79): 1.95e-10: 60: 18.84
+	Dm
		1477954 Q9W4I4_DROME (81-137): 3.68e-23: 91.8: 43.86		Q9VJ00_DROME (12-79): 2.71e-10: 59.6: 18.84
+	Dm
		118274 Q9W4I4_DROME (81-137): 3.68e-23: 91.8: 43.86		M9NCY1_DROME (12-79): 6.27e-10: 58.5: 18.84