HitPredict

Interactor 1: TAL1 (P22091)
T-cell acute lymphocytic leukemia protein 1 homolog (TAL-1) (Stem cell protein)
Gene: TAL1

Interactor 2: LMO3 (Q8BZL8)
LIM domain only protein 3 (LMO-3) (Neuronal-specific transcription factor DAT1)
Gene: LMO3

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	20211142
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	HLH~LIM
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 329 Mm			1 145
+	Mm
		644244 TAL1_MOUSE (1-329): 1.38e-88: 270: 100.00		RBTN2_MOUSE (13-133): 6e-46: 148: 60.33
+	Hs
		605169 TAL1_HUMAN (1-329): 1.21e-85: 262: 92.15		RBTN2_HUMAN (13-133): 8.24e-46: 148: 60.33
+	Hs
		605170 TAL1_HUMAN (1-329): 1.21e-85: 262: 92.15		RBTN1_HUMAN (1-133): 4.57e-36: 123: 95.49
+	Hs
		1229352 FIGLA_HUMAN (120-305): 4.53e-28: 110: 21.47		LHX8_HUMAN (12-132): 3.06e-46: 155: 39.67
+	Hs
		558956 LYL1_HUMAN (95-299): 3.83e-28: 112: 43.60		RBTN2_HUMAN (13-133): 8.24e-46: 148: 60.33
+	Hs
		1246450 FIGLA_HUMAN (120-305): 4.53e-28: 110: 21.47		LHX6_HUMAN (3-137): 8.87e-42: 143: 36.30
+	Hs
		681821 TAL2_HUMAN (186-297): 2.04e-27: 105: 46.43		RBTN2_HUMAN (13-133): 8.24e-46: 148: 60.33
+	Dm
		84289 DIMM_DROME (127-326): 1.79e-29: 118: 20.10		APTE_DROME (13-144): 1.06e-36: 132: 34.85
+	Hs
		223960 TCF21_HUMAN (155-270): 1.03e-27: 108: 33.61		LMO4_HUMAN (11-142): 2.91e-41: 137: 50.76
+	Hs
		681791 HEN1_HUMAN (189-244): 1.04e-21: 91: 60.71		RBTN2_HUMAN (13-133): 8.24e-46: 148: 60.33
+	Mm
		1223978 TAL2_MOUSE (186-297): 1.9e-27: 105: 48.21		RBTN1_MOUSE (1-145): 8.6e-40: 132: 89.66
+	Hs
		558957 LYL1_HUMAN (95-299): 3.83e-28: 112: 43.60		RBTN1_HUMAN (1-133): 4.57e-36: 123: 95.49
+	Mm
		1223977 TAL2_MOUSE (186-297): 1.9e-27: 105: 48.21		LMO3_MOUSE (1-145): 2.03e-36: 123: 100.00
+	Hs
		682035 TAL2_HUMAN (186-297): 2.04e-27: 105: 46.43		RBTN1_HUMAN (1-133): 4.57e-36: 123: 95.49
+	Dm
		1465666 Q9VHG3_DROME (96-273): 2.45e-27: 109: 22.91		Q9V472_DROME (72-144): 2.07e-11: 62.3: 23.29
+	Dm
		120449 Q9VHG3_DROME (96-273): 2.45e-27: 109: 22.91		M9PD53_DROME (75-144): 3.52e-11: 61.5: 21.43
+	Hs
		1246449 FIGLA_HUMAN (120-305): 4.53e-28: 110: 21.47		LHX3_HUMAN (4-74): 9.36e-11: 60: 19.44
+	Dm
		1477954 Q9W4I4_DROME (189-244): 2.89e-21: 90.6: 57.14		Q9VJ00_DROME (75-144): 5.01e-11: 61.2: 21.43
+	Dm
		118274 Q9W4I4_DROME (189-244): 2.89e-21: 90.6: 57.14		M9NCY1_DROME (4-79): 1.08e-10: 60: 19.48