HitPredict

Interactor 1: RBTN2 (P25791)
Rhombotin-2 (Cysteine-rich protein TTG-2) (LIM domain only protein 2) (LMO-2) (T-cell translocation protein 2)
Gene: LMO2

Interactor 2: HEN1 (Q02575)
Helix-loop-helix protein 1 (HEN-1) (Class A basic helix-loop-helix protein 35) (bHLHa35) (Nescient helix loop helix 1) (NSCL-1)
Gene: NHLH1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	12878195
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HLH~LIM
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 158 Hs			1 133
+	Hs
		558956 RBTN2_HUMAN (1-158): 5.59e-42: 138: 100.00		LYL1_HUMAN (3-132): 3.9e-26: 100: 33.08
+	Hs
		681821 RBTN2_HUMAN (1-158): 5.59e-42: 138: 100.00		TAL2_HUMAN (74-131): 2.78e-25: 94: 56.90
+	Hs
		558957 RBTN1_HUMAN (20-150): 3.92e-39: 131: 55.73		LYL1_HUMAN (3-132): 3.9e-26: 100: 33.08
+	Hs
		223960 LMO4_HUMAN (11-147): 1.13e-38: 130: 42.34		TCF21_HUMAN (2-131): 3.45e-26: 98.3: 29.32
+	Hs
		581779 LMO3_HUMAN (30-156): 6.25e-39: 130: 58.27		MYOG_HUMAN (5-131): 1.79e-24: 95.2: 26.77
+	Hs
		682035 RBTN1_HUMAN (20-150): 3.92e-39: 131: 55.73		TAL2_HUMAN (74-131): 2.78e-25: 94: 56.90
+	Mm
		644244 RBTN2_MOUSE (1-158): 4.12e-42: 139: 99.37		TAL1_MOUSE (76-132): 6.12e-20: 84.9: 59.65
+	Hs
		605169 RBTN2_HUMAN (1-158): 5.59e-42: 138: 100.00		TAL1_HUMAN (76-132): 3.38e-20: 85.7: 59.65
+	Mm
		1223977 LMO3_MOUSE (30-156): 6.25e-39: 130: 58.27		TAL2_MOUSE (81-131): 1.55e-23: 89.6: 64.71
+	Mm
		1223978 RBTN1_MOUSE (20-150): 7.05e-39: 130: 55.73		TAL2_MOUSE (81-131): 1.55e-23: 89.6: 64.71
+	Hs
		605170 RBTN1_HUMAN (20-150): 3.92e-39: 131: 55.73		TAL1_HUMAN (76-132): 3.38e-20: 85.7: 59.65
+	Mm
		644382 LMO3_MOUSE (30-156): 6.25e-39: 130: 58.27		TAL1_MOUSE (76-132): 6.12e-20: 84.9: 59.65
+	Dm
		120449 M9PD53_DROME (2-86): 8.62e-15: 72.3: 17.44		Q9VHG3_DROME (12-132): 1.41e-26: 101: 29.10
+	Dm
		1477954 Q9VJ00_DROME (2-86): 1.18e-14: 71.9: 17.44		Q9W4I4_DROME (54-132): 6.73e-26: 97.1: 84.81
+	Dm
		1465666 Q9V472_DROME (94-155): 8.13e-10: 58: 22.58		Q9VHG3_DROME (12-132): 1.41e-26: 101: 29.10
+	Dm
		118274 M9NCY1_DROME (89-155): 9.64e-10: 57.6: 17.91		Q9W4I4_DROME (54-132): 6.73e-26: 97.1: 84.81