HitPredict

Interactor 1: KPRB (O60256)
Phosphoribosyl pyrophosphate synthase-associated protein 2 (PRPP synthase-associated protein 2) (41 kDa phosphoribosypyrophosphate synthetase-associated protein) (PAP41)
Gene: PRPSAP2

Interactor 2: KPCG (P05129)
Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)
Gene: PRKCG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 369 Hs			1 697
+	Hs
		397153 PRPS1_HUMAN (17-367): 4.15e-171: 481: 43.75		KPCG_HUMAN (1-697): 0: 772: 100.00
+	Hs
		397131 PRPS2_HUMAN (17-367): 4.35e-169: 476: 44.32		KPCG_HUMAN (1-697): 0: 772: 100.00
+	Hs
		225840 KPRB_HUMAN (1-369): 0: 511: 100.00		KPCA_HUMAN (1-683): 0: 725: 70.03
+	Hs
		397163 KPRA_HUMAN (13-369): 1.56e-163: 463: 78.15		KPCG_HUMAN (1-697): 0: 772: 100.00
+	Hs
		566343 PRPS1_HUMAN (17-367): 4.15e-171: 481: 43.75		KPCA_HUMAN (1-683): 0: 725: 70.03
+	Hs
		515799 PRPS2_HUMAN (17-367): 4.35e-169: 476: 44.32		KPCA_HUMAN (1-683): 0: 725: 70.03
+	Hs
		566390 KPRA_HUMAN (13-369): 1.56e-163: 463: 78.15		KPCA_HUMAN (1-683): 0: 725: 70.03
+	Sc
		623466 KPR2_YEAST (15-367): 2.76e-151: 431: 38.48		KPC1_YEAST (17-680): 0: 556: 28.24
+	Hs
		225878 KPRB_HUMAN (1-369): 0: 511: 100.00		KPCD1_HUMAN (24-669): 6.8e-150: 460: 18.39
+	Hs
		893355 PRPS1_HUMAN (17-367): 4.15e-171: 481: 43.75		KPCD1_HUMAN (24-669): 6.8e-150: 460: 18.39
+	Hs
		515860 PRPS2_HUMAN (17-367): 4.35e-169: 476: 44.32		KPCD1_HUMAN (24-669): 6.8e-150: 460: 18.39
+	Hs
		1055329 KPRA_HUMAN (13-369): 1.56e-163: 463: 78.15		KPCD1_HUMAN (24-669): 6.8e-150: 460: 18.39
+	Hs
		225866 KPRB_HUMAN (1-369): 0: 511: 100.00		KPCE_HUMAN (3-262): 3.13e-57: 209: 34.07
+	Hs
		515835 PRPS2_HUMAN (17-367): 4.35e-169: 476: 44.32		KPCE_HUMAN (3-262): 3.13e-57: 209: 34.07
+	Hs
		225870 KPRB_HUMAN (1-369): 0: 511: 100.00		KPCZ_HUMAN (21-85): 2.64e-10: 65.5: 36.92