HitPredict

Interactor 1: SYK (Q15046)
Lysine--tRNA ligase (EC 2.7.7.-) (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS)
Gene: KARS1

Interactor 2: LMTK1 (Q6ZMQ8)
Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-binding protein) (p35BP)
Gene: AATK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 597 Hs			1 1374
+	Hs
		1065541 SYK_HUMAN (1-597): 0: 765: 100.00		LMTK2_HUMAN (9-1366): 0: 690: 29.74
+	Hs
		1065566 SYK_HUMAN (1-597): 0: 765: 100.00		LMTK3_HUMAN (7-1342): 9.67e-159: 518: 29.10
+	Hs
		609292 SYK_HUMAN (1-597): 0: 765: 100.00		FGFR3_HUMAN (29-448): 5.82e-123: 403: 23.42
+	Hs
		508007 SYK_HUMAN (1-597): 0: 765: 100.00		FGFR1_HUMAN (28-460): 6.26e-120: 396: 21.00
+	Hs
		384870 SYK_HUMAN (1-597): 0: 765: 100.00		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		213790 SYNC_HUMAN (12-572): 2.19e-146: 435: 18.18		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		384203 SYDC_HUMAN (116-572): 6.4e-133: 399: 19.63		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		385024 SYDM_HUMAN (185-358): 1.32e-13: 75.9: 31.46		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77