HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: STABP (O95630)
STAM-binding protein (EC 3.4.19.-) (Associated molecule with the SH3 domain of STAM) (Endosome-associated ubiquitin isopeptidase)
Gene: STAMBP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	35256949, 32814053
Identification Methods	affinity chromatography technology, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	JAB~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 424
+	Hs
		317702 UBB_HUMAN (1-234): 1.14e-59: 197: 17.92		STABP_HUMAN (1-424): 0: 605: 100.00
+	Hs
		317703 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		STABP_HUMAN (1-424): 0: 605: 100.00
+	Hs
		476192 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		STALP_HUMAN (1-424): 0: 583: 55.81
+	At
		1091838 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		AMSH1_ARATH (16-424): 7.05e-154: 446: 25.40
+	Sp
		477575 UBI4P_SCHPO (1-76): 1.1e-29: 121: 31.58		SST2_SCHPO (18-424): 2.28e-153: 443: 31.51