HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: RBMX (P38159)
RNA-binding motif protein, X chromosome (Glycoprotein p43) (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G) [Cleaved into: RNA-binding motif protein, X chromosome, N-terminally processed]
Gene: RBMX

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 465 Hs			1 391
+	Hs
		227414 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CIRBP_HUMAN (4-144): 1.3e-31: 119: 46.00
+	Hs
		226635 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TIA1_HUMAN (2-371): 9.39e-25: 106: 14.81
+	Hs
		227354 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP4_HUMAN (9-98): 1.43e-19: 92.6: 28.89
+	Hs
		227642 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PAP1L_HUMAN (9-220): 3.94e-19: 91: 18.52
+	Hs
		227193 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TIAR_HUMAN (1-344): 2.52e-18: 87.6: 15.23
+	Hs
		226375 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP1_HUMAN (6-93): 1.47e-17: 86.4: 27.27
+	Hs
		228332 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		DAZP1_HUMAN (9-136): 1.44e-17: 85.6: 27.34
+	Hs
		228678 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP3_HUMAN (6-93): 1.58e-15: 80.3: 23.86
+	Hs
		745216 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00
+	Hs
		1031383 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		PABP4_HUMAN (9-98): 1.43e-19: 92.6: 28.89
+	Hs
		267559 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		RMXL2_HUMAN (1-391): 9.4e-39: 144: 70.46
+	Hs
		312602 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		CIRBP_HUMAN (4-144): 1.3e-31: 119: 46.00
+	Hs
		312493 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		TIA1_HUMAN (2-371): 9.39e-25: 106: 14.81
+	Hs
		312462 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		PABP1_HUMAN (6-93): 1.47e-17: 86.4: 27.27
+	Hs
		312642 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		DAZP1_HUMAN (9-136): 1.44e-17: 85.6: 27.34
+	Hs
		475739 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		CIRBP_HUMAN (4-144): 1.3e-31: 119: 46.00
+	Hs
		475708 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP4_HUMAN (9-98): 1.43e-19: 92.6: 28.89
+	Hs
		475288 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP1_HUMAN (6-93): 1.47e-17: 86.4: 27.27
+	At
		186465 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		PABP4_ARATH (8-83): 1.86e-14: 76.8: 27.63
+	Hs
		475631 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		RBM3_HUMAN (8-88): 3.03e-15: 74.3: 55.56