HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: PCH2 (Q15645)
Pachytene checkpoint protein 2 homolog (Human papillomavirus type 16 E1 protein-binding protein) (16E1-BP) (HPV16 E1 protein-binding protein) (Thyroid hormone receptor interactor 13) (Thyroid receptor-interacting protein 13) (TR-interacting protein 13) (TRIP-13)
Gene: TRIP13

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.932

The method score is based on:

Property Details
Experiments 16189514, 35509820, 35256949, 19060904, 24722188
Identification Methods two hybrid, affinity chromatography technology, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~ubiquitin
Common GO terms GO:0005634 - nucleus
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 465
Hs

1 432
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024