Protein: SPOPL
Speckle-type POZ protein-like (HIB homolog 2) (Roadkill homolog 2)

Gene: SPOPL
Organism: Homo sapiens
Interactions: 17
UniProt ID: Q6IQ16

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0016567 - protein ubiquitination
GO:0030162 - regulation of proteolysis
GO:0031397 - negative regulation of protein ubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

227589

SPOP
Speckle-type POZ protein

2

15

Small-scale

0.799

High

179056

IMA6
Importin subunit alpha-6

3

9

High-throughput

0.675

High

1113397

CUL3
Cullin-3

1

20

Small-scale

0.647

High

1234755

SPOPL
Speckle-type POZ protein-like

1

14

Small-scale

0.647

High

583572

ATF2
Cyclic AMP-dependent transcription factor ATF-2

2

5

High-throughput

0.606

High

704537

RXRB
Retinoic acid receptor RXR-beta

2

6

High-throughput

0.606

High

1039765

CREB5
Cyclic AMP-responsive element-binding protein 5

2

5

High-throughput

0.606

High

1234758

MYD88
Myeloid differentiation primary response protein MyD88

2

6

High-throughput

0.606

High

1234761

ANFY1
Rabankyrin-5

1

0

High-throughput

0.578

High

839777

EPS15
Epidermal growth factor receptor substrate 15

1

6

Small-scale

0.578

High

1234756

HOME1
Homer protein homolog 1

1

5

High-throughput

0.536

High

1234759

HOME2
Homer protein homolog 2

1

4

High-throughput

0.536

High

1234760

HOME3
Homer protein homolog 3

1

7

High-throughput

0.536

High

1234762

GT2D1
General transcription factor II-I repeat domain-containing protein 1

1

0

High-throughput

0.513

High

1234763

NUP50
Nuclear pore complex protein Nup50

1

5

High-throughput

0.489

High

1234757

BBS5
BBSome complex member BBS5

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025