HitPredict

Interactor 1: EDEM3 (Q9BZQ6)
ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3)
Gene: EDEM3

Interactor 2: SE1L1 (Q9UBV2)
Protein sel-1 homolog 1 (Suppressor of lin-12-like protein 1) (Sel-1L)
Gene: SEL1L

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	24910992, 28366632
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0036503 - ERAD pathway
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 932 Hs			1 794
+	Hs
		1285503 EDEM3_HUMAN (1-932): 0: 1458: 100.00		ESPB1_HUMAN (64-168): 2.27e-20: 92.7: 30.48
+	Hs
		1313612 EDEM2_HUMAN (19-535): 0: 618: 37.62		SE1L1_HUMAN (1-794): 0: 752: 100.00
+	Hs
		1268026 EDEM1_HUMAN (43-514): 0: 605: 42.42		SE1L1_HUMAN (1-794): 0: 752: 100.00
+	Hs
		1285502 EDEM2_HUMAN (19-535): 0: 618: 37.62		ESPB1_HUMAN (64-168): 2.27e-20: 92.7: 30.48