HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: GP141 (Q7Z602)
Probable G-protein coupled receptor 141 (G-protein coupled receptor PGR13)
Gene: GPR141

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 305
+	Hs
		226674 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ADA1B_HUMAN (3-302): 2.6e-67: 220: 13.26
+	Hs
		428888 UBB_HUMAN (1-234): 1.14e-59: 197: 17.92		ADRB2_HUMAN (2-304): 3.82e-67: 216: 14.03
+	Hs
		475549 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		CXCR4_HUMAN (10-298): 1.82e-70: 223: 18.64
+	Hs
		428889 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		ADRB2_HUMAN (2-304): 3.82e-67: 216: 14.03
+	Hs
		475412 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		OPRM_HUMAN (3-298): 5.46e-67: 216: 17.88
+	Dm
		1374837 Q9W418_DROME (1-77): 5.42e-30: 124: 32.47		Q9VVQ1_DROME (3-300): 6.46e-64: 210: 16.56