HitPredict

Interactor 1: KALRN (A2CG49)
Kalirin (EC 2.7.11.1) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain)
Gene: KALRN

Interactor 2: D3YZ62 (D3YZ62)
Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle)
Gene: Myo5a

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28706196
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Myosin_head~Spectrin
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2964 Mm			1 1828
+	Mm
		60120 KALRN_MOUSE (1-2964): 0: 2425: 100.00		MYO5A_MOUSE (1-1828): 0: 1285: 98.65
+	Hs
		299581 TRIO_HUMAN (4-2954): 0: 2113: 60.20		MYO10_HUMAN (7-994): 0: 874: 30.00
+	Hs
		1028918 SPTB2_HUMAN (83-1594): 2.04e-83: 309: 12.46		MYO5A_HUMAN (1-1828): 0: 1268: 95.47
+	Hs
		920529 DAPK1_HUMAN (2645-2914): 4.8e-62: 238: 41.37		MYO5B_HUMAN (1-1828): 0: 1157: 60.49
+	Hs
		1153030 MYLK_HUMAN (2077-2550): 1.32e-19: 99.6: 17.44		MYO5A_HUMAN (1-1828): 0: 1268: 95.47
+	Hs
		1028889 SPTB2_HUMAN (83-1594): 2.04e-83: 309: 12.46		MYO5C_HUMAN (1-1828): 0: 1048: 48.72
+	Hs
		1117500 SPTN1_HUMAN (95-1138): 4.49e-68: 259: 13.16		MYO5C_HUMAN (1-1828): 0: 1048: 48.72
+	Dm
		52562 Q9VZQ3_DROME (157-1428): 8.22e-86: 318: 13.24		A1Z6Z9_DROME (2-1824): 0: 965: 38.54
+	Dm
		52513 SPTCB_DROME (134-1578): 2.24e-84: 312: 12.05		A1Z6Z9_DROME (2-1824): 0: 965: 38.54
+	Hs
		212690 DAPK3_HUMAN (2649-2911): 2.04e-62: 223: 40.59		MYO5C_HUMAN (1-1828): 0: 1048: 48.72
+	Dm
		52499 SPTCA_DROME (115-1105): 1.21e-70: 267: 14.73		A1Z6Z9_DROME (2-1824): 0: 965: 38.54
+	Hs
		227836 DAPK1_HUMAN (2645-2914): 4.8e-62: 238: 41.37		MYO1B_HUMAN (66-914): 6.34e-152: 500: 35.86
+	Hs
		772748 SPTB2_HUMAN (83-1594): 2.04e-83: 309: 12.46		MYH9_HUMAN (756-1476): 1.68e-31: 137: 11.46
+	Hs
		174713 SPTN2_HUMAN (145-1906): 1.12e-78: 294: 11.66		MYH9_HUMAN (756-1476): 1.68e-31: 137: 11.46
+	Hs
		772789 SPTN1_HUMAN (95-1138): 4.49e-68: 259: 13.16		MYH9_HUMAN (756-1476): 1.68e-31: 137: 11.46
+	Hs
		556923 SPTN1_HUMAN (95-1138): 4.49e-68: 259: 13.16		MYH7_HUMAN (699-1442): 1.73e-30: 134: 11.60
+	Hs
		212639 DAPK3_HUMAN (2649-2911): 2.04e-62: 223: 40.59		MYH9_HUMAN (756-1476): 1.68e-31: 137: 11.46
+	Hs
		116295 H3BPE1_HUMAN (79-1311): 1.13e-24: 116: 9.78		MYH9_HUMAN (756-1476): 1.68e-31: 137: 11.46
+	Hs
		773085 MACF1_HUMAN (79-1221): 3.49e-24: 115: 10.06		MYH9_HUMAN (756-1476): 1.68e-31: 137: 11.46
+	Hs
		772822 MYLK_HUMAN (2077-2550): 1.32e-19: 99.6: 17.44		MYH9_HUMAN (756-1476): 1.68e-31: 137: 11.46