Interactor 1: AKAP8 (O43823)
A-kinase anchor protein 8 (AKAP-8) (A-kinase anchor protein 95 kDa) (AKAP 95)
Gene: AKAP8
Interactor 2: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.77 | 0.60 | 0.683 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31527615, 33731348, 21182205, unassigned1953 |
| Identification Methods | affinity chromatography technology, tandem affinity purification, cosedimentation through density gradient |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0007165 - signal transduction GO:0008270 - zinc ion binding and 1 others more... |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025