HitPredict

Interactor 1: AIRE (O43918)
Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein)
Gene: AIRE

Interactor 2: TBB4B (P68371)
Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain)
Gene: TUBB4B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23443559
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 545 Hs			1 445
+	Hs
		231082 AIRE_HUMAN (1-545): 1.25e-134: 403: 100.00		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		1102818 SP140_HUMAN (5-307): 1.72e-35: 143: 16.61		TBB6_HUMAN (1-432): 0: 706: 92.36
+	Hs
		457444 CHD4_HUMAN (74-489): 2.07e-30: 128: 13.43		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		997343 CHD4_HUMAN (74-489): 2.07e-30: 128: 13.43		TBB4B_HUMAN (1-427): 0: 711: 100.00
+	Hs
		457633 UHRF1_HUMAN (268-410): 2.96e-28: 121: 23.87		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		1403647 UHRF1_HUMAN (268-410): 2.96e-28: 121: 23.87		TBB2B_HUMAN (1-430): 0: 710: 98.14
+	Hs
		457396 CHD3_HUMAN (74-503): 9.27e-27: 117: 14.16		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		997303 CHD3_HUMAN (74-503): 9.27e-27: 117: 14.16		TBB4B_HUMAN (1-427): 0: 711: 100.00
+	Hs
		408140 UHRF1_HUMAN (268-410): 2.96e-28: 121: 23.87		TBB4A_HUMAN (1-427): 0: 706: 98.60
+	Hs
		457773 TRI33_HUMAN (336-540): 1.26e-16: 85.6: 16.13		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		1191943 PHF12_HUMAN (295-340): 4.72e-09: 61.2: 54.17		TBB8_HUMAN (1-427): 0: 696: 91.10