Protein: PHF12
PHD finger protein 12 (PHD factor 1) (Pf1)

Gene: PHF12
Organism: Homo sapiens
Interactions: 108
UniProt ID: Q96QT6

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001222 - transcription corepressor binding
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1401056

MO4L1
Mortality factor 4-like protein 1

15

6

Small-scale

0.985

High

1136842

MO4L2
Mortality factor 4-like protein 2

9

6

Small-scale

0.969

High

1110005

HDAC1
Histone deacetylase 1

8

20

Small-scale

0.968

High

274369

SIN3B
Paired amphipathic helix protein Sin3b

4

17

High-throughput

0.895

High

711838

KDM5A
Lysine-specific demethylase 5A

3

9

High-throughput

0.861

High

1368065

HDAC2
Histone deacetylase 2

3

20

High-throughput

0.847

High

1401040

SIN3A
Paired amphipathic helix protein Sin3a

2

17

Small-scale

0.826

High

1158967

RBBP7
Histone-binding protein RBBP7

7

20

High-throughput

0.745

High

1357142

GATD1
GATA zinc finger domain-containing protein 1

6

3

High-throughput

0.733

High

1163153

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.691

High

1066452

RBBP4
Histone-binding protein RBBP4

3

20

High-throughput

0.667

High

1278963

EMSY
BRCA2-interacting transcriptional repressor EMSY

3

16

High-throughput

0.656

High

211399

RFOX2
RNA binding protein fox-1 homolog 2

1

14

High-throughput

0.618

High

277785

H2AY
Core histone macro-H2A.1

1

20

High-throughput

0.618

High

316952

MTA2
Metastasis-associated protein MTA2

1

20

High-throughput

0.618

High

998706

H31
Histone H3.1

1

20

High-throughput

0.618

High

1086807

BPTF
Nucleosome-remodeling factor subunit BPTF

1

20

High-throughput

0.618

High

1088517

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

17

High-throughput

0.618

High

1186501

CHD9
Chromodomain-helicase-DNA-binding protein 9

1

20

High-throughput

0.618

High

1195586

ARI4B
AT-rich interactive domain-containing protein 4B

1

20

High-throughput

0.618

High

1351282

CHD5
Chromodomain-helicase-DNA-binding protein 5

1

17

High-throughput

0.618

High

1384417

PF21A
PHD finger protein 21A

1

18

High-throughput

0.618

High

1401038

PHF12
PHD finger protein 12

1

19

High-throughput

0.618

High

1401044

MTA3
Metastasis-associated protein MTA3

1

20

High-throughput

0.618

High

1401047

BRD8
Bromodomain-containing protein 8

1

17

High-throughput

0.618

High

1401053

RFOX1
RNA binding protein fox-1 homolog 1

1

17

High-throughput

0.618

High

1401062

BRPF3
Bromodomain and PHD finger-containing protein 3

1

20

High-throughput

0.618

High

1119599

NFYC
Nuclear transcription factor Y subunit gamma

1

0

High-throughput

0.586

High

282293

SAP30
Histone deacetylase complex subunit SAP30

2

5

Small-scale

0.584

High

1133616

NFIX
Nuclear factor 1 X-type

2

20

High-throughput

0.584

High

396755

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1401046

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

6

High-throughput

0.541

High

686856

S10A4
Protein S100-A4

1

16

High-throughput

0.536

High

1162009

H31T
Histone H3.1t

1

20

High-throughput

0.527

High

799413

BRCA1
Breast cancer type 1 susceptibility protein

1

11

High-throughput

0.481

High

143204

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

155344

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

9

High-throughput

0.479

High

246880

KDM1A
Lysine-specific histone demethylase 1A

1

15

High-throughput

0.479

High

255674

DPM1
Dolichol-phosphate mannosyltransferase subunit 1

1

1

High-throughput

0.479

High

339831

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.479

High

372900

MYC
Myc proto-oncogene protein

1

15

High-throughput

0.479

High

404349

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

415801

HSPB1
Heat shock protein beta-1

1

5

High-throughput

0.479

High

474225

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

519550

MYBB
Myb-related protein B

1

7

High-throughput

0.479

High

520305

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

538460

EGR2
E3 SUMO-protein ligase EGR2

1

20

High-throughput

0.479

High

577490

ETS1
Protein C-ets-1

1

20

High-throughput

0.479

High

675639

TYY1
Transcriptional repressor protein YY1

1

20

High-throughput

0.479

High

685318

PAX6
Paired box protein Pax-6

1

11

High-throughput

0.479

High

739020

ELF1
ETS-related transcription factor Elf-1

1

20

High-throughput

0.479

High

786795

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

8

High-throughput

0.479

High

834035

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.479

High

837080

ELK3
ETS domain-containing protein Elk-3

1

20

High-throughput

0.479

High

887143

CEBPA
CCAAT/enhancer-binding protein alpha

1

14

High-throughput

0.479

High

913799

ZN131
Zinc finger protein 131

1

20

High-throughput

0.479

High

913895

ZN143
Zinc finger protein 143

1

14

High-throughput

0.479

High

944725

KLF3
Krueppel-like factor 3

1

20

High-throughput

0.479

High

980175

H4
Histone H4

1

15

High-throughput

0.479

High

1029141

E2F1
Transcription factor E2F1

1

4

High-throughput

0.479

High

1087959

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1118670

KLF9
Krueppel-like factor 9

1

20

High-throughput

0.479

High

1118762

KLF5
Krueppel-like factor 5

1

20

High-throughput

0.479

High

1126863

NF2L1
Endoplasmic reticulum membrane sensor NFE2L1

1

11

High-throughput

0.479

High

1129705

MDC1
Mediator of DNA damage checkpoint protein 1

1

19

High-throughput

0.479

High

1152729

ELF2
ETS-related transcription factor Elf-2

1

20

High-throughput

0.479

High

1208632

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

10

High-throughput

0.479

High

1216622

LIN9
Protein lin-9 homolog

1

4

High-throughput

0.479

High

1276669

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

13

High-throughput

0.479

High

1312684

BAP18
BPTF-associated chromatin complex component 1

1

5

High-throughput

0.479

High

1338911

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.479

High

1360992

P66B
Transcriptional repressor p66-beta

1

10

High-throughput

0.479

High

1367070

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1379934

LHX4
LIM/homeobox protein Lhx4

1

12

High-throughput

0.479

High

1387506

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

17

High-throughput

0.479

High

1389871

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

1

High-throughput

0.479

High

1392559

LIN37
Protein lin-37 homolog

1

4

High-throughput

0.479

High

1398764

PWP2A
PWWP domain-containing protein 2A

1

13

High-throughput

0.479

High

1401039

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1401041

FEV
Protein FEV

1

20

High-throughput

0.479

High

1401042

ELF4
ETS-related transcription factor Elf-4

1

20

High-throughput

0.479

High

1401043

KLF6
Krueppel-like factor 6

1

20

High-throughput

0.479

High

1401045

KLF16
Krueppel-like factor 16

1

20

High-throughput

0.479

High

1401048

BC11A
BCL11 transcription factor A

1

18

High-throughput

0.479

High

1401049

ZN335
Zinc finger protein 335

1

9

High-throughput

0.479

High

1401050

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

10

High-throughput

0.479

High

1401054

SENP1
Sentrin-specific protease 1

1

3

High-throughput

0.479

High

1401055

MBD2
Methyl-CpG-binding domain protein 2

1

19

High-throughput

0.479

High

1401059

KLF15
Krueppel-like factor 15

1

20

High-throughput

0.479

High

1401060

GPTC8
G patch domain-containing protein 8

1

20

High-throughput

0.479

High

1401061

RCOR1
REST corepressor 1

1

20

High-throughput

0.479

High

1401064

ZN281
Zinc finger protein 281

1

9

High-throughput

0.479

High

1401065

KLF12
Krueppel-like factor 12

1

20

High-throughput

0.479

High

1294952

PALB2
Partner and localizer of BRCA2

1

0

High-throughput

0.458

High

1401052

MRGBP
MRG/MORF4L-binding protein

1

0

High-throughput

0.458

High

1401063

ABCG2
Broad substrate specificity ATP-binding cassette transporter ABCG2

1

0

High-throughput

0.458

High

1401066

MOFA1
MORF4 family-associated protein 1

1

0

High-throughput

0.458

High

1401051

LN28A
Protein lin-28 homolog A

1

3

High-throughput

0.445

High

347264

BAG2
BAG family molecular chaperone regulator 2

1

5

High-throughput

0.437

High

997090

TBA4A
Tubulin alpha-4A chain

1

9

High-throughput

0.437

High

1178143

QSER1
Glutamine and serine-rich protein 1

1

19

High-throughput

0.437

High

1191943

TBB8
Tubulin beta-8 chain

1

8

High-throughput

0.437

High

1401057

ABCF2
ATP-binding cassette sub-family F member 2

1

2

High-throughput

0.437

High

1401058

HMGX4
HMG domain-containing protein 4

1

20

High-throughput

0.437

High

1331443

VA0D2
V-type proton ATPase subunit d 2

2

0

High-throughput

0.316

High

1322428

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.279

Low

991913

DYLT1
Dynein light chain Tctex-type 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025