HitPredict

Interactor 1: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A

Interactor 2: ZN516 (Q92618)
Zinc finger protein 516
Gene: ZNF516

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	34079125, 34709266, 16079794, 28947780
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0120162 - positive regulation of cold-induced thermogenesis GO:0140297 - DNA-binding transcription factor binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 852 Hs			1 1163
+	Mm
		1169711 KDM1A_MOUSE (1-852): 0: 922: 97.30		ZN516_MOUSE (90-1162): 0: 1060: 72.94
+	Hs
		232349 KDM1A_HUMAN (1-852): 0: 936: 100.00		ZFP28_HUMAN (143-537): 6.55e-85: 297: 19.07
+	Hs
		231909 KDM1A_HUMAN (1-852): 0: 936: 100.00		ZN217_HUMAN (169-600): 3.48e-51: 199: 33.95
+	Mm
		1112180 KDM1A_MOUSE (1-852): 0: 922: 97.30		Q3U0X6_MOUSE (158-600): 5.21e-48: 188: 32.53