Interactor 1: ROCK2 (O75116)
Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)
Gene: ROCK2

Interactor 2: ROCK2 (O75116)
Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)
Gene: ROCK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 39358380
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase, Rho_Binding~Rho_Binding
Common GO terms GO:0000281 - mitotic cytokinesis
GO:0001837 - epithelial to mesenchymal transition
GO:0001934 - positive regulation of protein phosphorylation
GO:0002020 - protease binding
GO:0002931 - response to ischemia
and 68 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1388
Hs

1 1388
+ Bt
+ Hs
+ Hs
+ Rn
+ Hs
+ Sp
+ At
+ At
+ At
+ At
+ At
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025