Interactor 1: APH1 (O45876)
Gamma-secretase subunit aph-1 (Anterior-pharynx-defective protein 1) (Presenilin enhancer protein 1)
Gene: aph-1
Interactor 2: PEN2 (Q9U357)
Gamma-secretase subunit pen-2 (Presenilin enhancer protein 2)
Gene: pen-2
Species: Caenorhabditis elegans
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.60 | 0.479 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15210705 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0007219 - Notch signaling pathway GO:0007220 - Notch receptor processing GO:0009792 - embryo development ending in birth or egg hatching GO:0045165 - cell fate commitment GO:0048598 - embryonic morphogenesis and 2 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
