Protein: APH1B
Gamma-secretase subunit APH-1B (APH-1b) (Aph-1beta) (Presenilin-stabilization factor-like)

Gene: APH1B
Organism: Homo sapiens
Interactions: 13
UniProt ID: Q8WW43

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0007219 - Notch signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

890759

PSN2
Presenilin-2

2

10

Small-scale

0.754

High

890023

PSN1
Presenilin-1

1

10

Small-scale

0.618

High

871002

T4S4
Transmembrane 4 L6 family member 4

2

0

High-throughput

0.580

High

1249502

VSTM1
V-set and transmembrane domain-containing protein 1

2

0

High-throughput

0.580

High

63683

A5PKU2
TUSC5 protein

1

3

High-throughput

0.515

High

422726

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.515

High

1312108

TARG1
Trafficking regulator of GLUT4 1

1

3

High-throughput

0.481

High

1359068

FXYD6
FXYD domain-containing ion transport regulator 6

1

1

High-throughput

0.481

High

1359067

NICA
Nicastrin

1

6

Small-scale

0.479

High

1359069

PEN2
Gamma-secretase subunit PEN-2

1

3

Small-scale

0.479

High

870278

S6A12
Sodium- and chloride-dependent betaine transporter

1

0

High-throughput

0.426

High

1324780

LAT4
Large neutral amino acids transporter small subunit 4

1

0

High-throughput

0.426

High

660285

BDNF
Neurotrophic factor BDNF precursor form

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025