HitPredict

Interactor 1: AT2A2 (O55143)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
Gene: Atp2a2

Interactor 2: AT2A2 (O55143)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
Gene: Atp2a2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 29199018
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cation_ATPase~E1-E2_ATPase, Cation_ATPase~Hydrolase, Cation_ATPase_C~Cation_ATPase_C, Cation_ATPase_C~E1-E2_ATPase, Cation_ATPase_C~Hydrolase, Cation_ATPase_N~E1-E2_ATPase, Cation_ATPase_N~Hydrolase, E1-E2_ATPase~E1-E2_ATPase, E1-E2_ATPase~Hydrolase, Hydrolase~Hydrolase
Common GO terms GO:0000045 - autophagosome assembly
GO:0002026 - regulation of the force of heart contraction
GO:0005246 - calcium channel regulator activity
GO:0005388 - P-type calcium transporter activity
GO:0005509 - calcium ion binding
and 32 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 1044
Mm

1 1044
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Last updated: 11Aug2025