Interactor 1: TLR5 (O60602)
Toll-like receptor 5 (Toll/interleukin-1 receptor-like protein 3)
Gene: TLR5

Interactor 2: IRAK4 (Q9NWZ3)
Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)
Gene: IRAK4

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 17138965, 16574867
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_8~PK_Tyr_Ser-Thr
Common GO terms GO:0002224 - toll-like receptor signaling pathway
GO:0005149 - interleukin-1 receptor binding
GO:0005886 - plasma membrane
GO:0045087 - innate immune response
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 858
Hs

1 460
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024