Interactor 1: HCN1 (O60741)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1)
Gene: HCN1

Interactor 2: RPGF4 (Q8WZA2)
Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII)
Gene: RAPGEF4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 0.90 0.546

The method score is based on:

Property Details
Experiments 37207277
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains cNMP_binding~cNMP_binding, RasGEF_N~cNMP_binding, Ion_trans~cNMP_binding, Ion_trans_N~cNMP_binding
Common GO terms GO:0005886 - plasma membrane
GO:0030552 - cAMP binding
Homologous interactions 0

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Last updated: 15 Jul 2024