HitPredict

Interactor 1: DPM1 (O60762)
Dolichol-phosphate mannosyltransferase subunit 1 (EC 2.4.1.83) (Dolichol-phosphate mannose synthase subunit 1) (DPM synthase subunit 1) (Dolichyl-phosphate beta-D-mannosyltransferase subunit 1) (Mannose-P-dolichol synthase subunit 1) (MPD synthase subunit 1)
Gene: DPM1

Interactor 2: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 260 Hs			1 1367
+	Hs
		872550 GLT16_HUMAN (8-238): 7.69e-76: 241: 16.80		EPHB4_HUMAN (648-1305): 5.48e-162: 514: 23.20
+	Hs
		240654 DPM1_HUMAN (1-260): 1.64e-93: 277: 100.00		ALK_HUMAN (939-1304): 2.51e-75: 278: 39.12
+	Hs
		240509 DPM1_HUMAN (1-260): 1.64e-93: 277: 100.00		NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61
+	Hs
		240529 DPM1_HUMAN (1-260): 1.64e-93: 277: 100.00		UFO_HUMAN (790-1271): 9.27e-68: 249: 32.10
+	Hs
		240588 DPM1_HUMAN (1-260): 1.64e-93: 277: 100.00		NTRK3_HUMAN (977-1262): 5.74e-64: 236: 39.16
+	Hs
		240523 DPM1_HUMAN (1-260): 1.64e-93: 277: 100.00		FGFR3_HUMAN (972-1266): 2.05e-63: 234: 38.44
+	Hs
		240514 DPM1_HUMAN (1-260): 1.64e-93: 277: 100.00		ROS1_HUMAN (691-919): 7.36e-11: 69.4: 17.47