Protein: RN19B
E3 ubiquitin-protein ligase RNF19B (EC 2.3.2.31) (IBR domain-containing protein 3) (Natural killer lytic-associated molecule) (RING finger protein 19B)

Gene: RN19B, RNF19B
Organism: Homo sapiens
Interactions: 84
UniProt ID: Q6ZMZ0

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0002250 - adaptive immune response
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

507240

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

19

High-throughput

0.811

High

995979

UB2L3
Ubiquitin-conjugating enzyme E2 L3

2

20

Small-scale

0.802

High

1252079

AP1M1
AP-1 complex subunit mu-1

4

7

High-throughput

0.698

High

168543

UB2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6

1

20

Small-scale

0.690

High

679356

DNJB2
DnaJ homolog subfamily B member 2

3

4

High-throughput

0.667

High

957106

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

20

Small-scale

0.647

High

982216

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

20

High-throughput

0.647

High

1252062

RN19B
E3 ubiquitin-protein ligase RNF19B

1

18

Small-scale

0.647

High

341088

DIRA3
GTP-binding protein Di-Ras3

4

10

Small-scale

0.633

High

136403

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

2

13

High-throughput

0.628

High

275900

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

2

8

High-throughput

0.628

High

699784

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

8

High-throughput

0.628

High

718585

CDC27
Cell division cycle protein 27 homolog

2

14

High-throughput

0.628

High

839039

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

2

7

High-throughput

0.628

High

839163

PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

2

7

High-throughput

0.628

High

967154

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

2

8

High-throughput

0.628

High

1094573

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

2

14

High-throughput

0.628

High

1108575

TBB3
Tubulin beta-3 chain

2

16

High-throughput

0.628

High

1219716

ZMYM4
Zinc finger MYM-type protein 4

2

10

High-throughput

0.628

High

1252063

VP13C
Intermembrane lipid transfer protein VPS13C

2

2

High-throughput

0.628

High

1252065

DEN6A
Protein DENND6A

2

1

High-throughput

0.628

High

1252066

PALS1
Protein PALS1

2

11

High-throughput

0.628

High

1252069

WDR48
WD repeat-containing protein 48

2

14

High-throughput

0.628

High

1252070

WDR20
WD repeat-containing protein 20

2

14

High-throughput

0.628

High

1252071

NEK9
Serine/threonine-protein kinase Nek9

2

11

High-throughput

0.628

High

1252075

VP13A
Intermembrane lipid transfer protein VPS13A

2

3

High-throughput

0.628

High

1252088

CPNE7
Copine-7

2

6

High-throughput

0.628

High

1252089

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

2

8

High-throughput

0.628

High

1252091

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

2

14

High-throughput

0.628

High

508163

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

19

High-throughput

0.618

High

643899

FBRL
rRNA 2'-O-methyltransferase fibrillarin

3

2

High-throughput

0.609

High

162217

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

2

1

High-throughput

0.606

High

571776

FPPS
Farnesyl pyrophosphate synthase

2

1

High-throughput

0.606

High

1043143

TAP1
Antigen peptide transporter 1

2

4

High-throughput

0.606

High

1148900

SC23A
Protein transport protein Sec23A

2

5

High-throughput

0.606

High

1204164

MEST
Mesoderm-specific transcript homolog protein

2

2

High-throughput

0.606

High

1252074

SC22A
Vesicle-trafficking protein SEC22a

2

3

High-throughput

0.606

High

1252083

SAC1
Phosphatidylinositol-3-phosphatase SAC1

2

4

High-throughput

0.606

High

317866

LTN1
E3 ubiquitin-protein ligase listerin

2

0

High-throughput

0.602

High

1177946

MOONR
Protein moonraker

2

0

High-throughput

0.602

High

1252080

WDR11
WD repeat-containing protein 11

2

0

High-throughput

0.602

High

160292

GOSR2
Golgi SNAP receptor complex member 2

2

0

High-throughput

0.580

High

254292

ICMT
Protein-S-isoprenylcysteine O-methyltransferase

2

0

High-throughput

0.580

High

331476

APOL3
Apolipoprotein L3

2

0

High-throughput

0.580

High

911842

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

2

0

High-throughput

0.580

High

1034947

PYRD
Dihydroorotate dehydrogenase

2

0

High-throughput

0.580

High

1252076

ZNT3
Probable proton-coupled zinc antiporter SLC30A3

2

0

High-throughput

0.580

High

1252077

TM208
Transmembrane protein 208

2

0

High-throughput

0.580

High

1252084

TM100
Transmembrane protein 100

2

0

High-throughput

0.580

High

1252092

SELK
Selenoprotein K

2

0

High-throughput

0.580

High

1187358

HSDL1
Inactive hydroxysteroid dehydrogenase-like protein 1

2

5

High-throughput

0.574

High

1252082

ST7
Suppressor of tumorigenicity 7 protein

2

1

High-throughput

0.574

High

1252090

AP3M1
AP-3 complex subunit mu-1

2

9

High-throughput

0.574

High

1252093

DDX49
Probable ATP-dependent RNA helicase DDX49

2

19

High-throughput

0.574

High

515701

TPC2B
Trafficking protein particle complex subunit 2B

2

0

High-throughput

0.559

High

252607

TSN2
Tetraspanin-2

2

1

High-throughput

0.553

High

378126

TNFA
Tumor necrosis factor

2

1

High-throughput

0.553

High

455915

ASGR1
Asialoglycoprotein receptor 1

2

2

High-throughput

0.553

High

1236193

MFSD5
Molybdate-anion transporter

2

1

High-throughput

0.553

High

1252067

CLC1A
C-type lectin domain family 1 member A

2

3

High-throughput

0.553

High

295596

CIB2
Calcium and integrin-binding family member 2

1

2

High-throughput

0.536

High

968640

NCS1
Neuronal calcium sensor 1

1

1

High-throughput

0.536

High

1228754

MBLC2
Acyl-coenzyme A thioesterase MBLAC2

1

1

High-throughput

0.536

High

1252064

ARL17
ADP-ribosylation factor-like protein 17

1

10

High-throughput

0.536

High

1252068

RN149
E3 ubiquitin-protein ligase RNF149

1

4

High-throughput

0.536

High

1252072

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

2

High-throughput

0.536

High

1252081

TOLIP
Toll-interacting protein

1

1

High-throughput

0.536

High

1252085

UCKL1
Uridine-cytidine kinase-like 1

1

1

Small-scale

0.529

High

1252086

BTG4
Protein BTG4

1

0

Small-scale

0.529

High

786686

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

6

Small-scale

0.508

High

1252078

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

2

High-throughput

0.489

High

461616

HS90A
Heat shock protein HSP 90-alpha

1

7

High-throughput

0.479

High

468517

HS90B
Heat shock protein HSP 90-beta

1

7

High-throughput

0.479

High

988465

RAC1
Ras-related C3 botulinum toxin substrate 1

1

6

Small-scale

0.479

High

1207700

TMM31
Transmembrane protein 31

1

1

High-throughput

0.439

High

1225933

F91A1
Protein FAM91A1

2

0

High-throughput

0.328

High

1252087

S53A1
Solute carrier family 53 member 1

2

0

High-throughput

0.328

High

49660

T120B
Transmembrane protein 120B

2

0

High-throughput

0.316

High

549451

CD20
B-lymphocyte antigen CD20

2

0

High-throughput

0.316

High

1068877

NIPA4
Magnesium transporter NIPA4

2

0

High-throughput

0.316

High

1252073

GIMA5
GTPase IMAP family member 5

2

0

High-throughput

0.316

High

329293

LETM1
Mitochondrial proton/calcium exchanger protein

1

0

High-throughput

0.279

Low

106140

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025