HitPredict

Interactor 1: H2B1K (O60814)
Histone H2B type 1-K (H2B K) (HIRA-interacting protein 1)
Gene: H2BC12

Interactor 2: PRC2A (P48634)
Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene: PRRC2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 2157
+	Hs
		820873 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00
+	Hs
		821000 H2B1H_HUMAN (1-126): 5.43e-54: 166: 98.41		PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00
+	Hs
		1127616 H2B2F_HUMAN (1-126): 2.19e-54: 168: 97.62		PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60
+	Hs
		241550 H2B1K_HUMAN (1-126): 1.2e-53: 166: 100.00		PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60
+	Hs
		918418 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60
+	Hs
		807749 H2B2F_HUMAN (1-126): 2.19e-54: 168: 97.62		MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83
+	Hs
		617932 H2B1O_HUMAN (1-126): 2.88e-54: 167: 97.62		MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83
+	Hs
		807817 H2B1M_HUMAN (1-126): 4.46e-54: 167: 96.03		MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83
+	Hs
		241473 H2B1K_HUMAN (1-126): 1.2e-53: 166: 100.00		MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83
+	Hs
		420812 H2B1J_HUMAN (1-126): 6.13e-54: 166: 99.21		MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83
+	Hs
		807677 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83
+	Hs
		807795 H2B1H_HUMAN (1-126): 5.43e-54: 166: 98.41		MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83
+	Hs
		1129830 H2B2F_HUMAN (1-126): 2.19e-54: 168: 97.62		TITIN_HUMAN (25-1264): 8.01e-19: 96.8: 11.60
+	Hs
		617962 H2B1O_HUMAN (1-126): 2.88e-54: 167: 97.62		TITIN_HUMAN (25-1264): 8.01e-19: 96.8: 11.60
+	Hs
		1264778 H2B1H_HUMAN (1-126): 5.43e-54: 166: 98.41		TITIN_HUMAN (25-1264): 8.01e-19: 96.8: 11.60
+	Hs
		241595 H2B1K_HUMAN (1-126): 1.2e-53: 166: 100.00		TITIN_HUMAN (25-1264): 8.01e-19: 96.8: 11.60
+	Hs
		1056919 H2B1H_HUMAN (1-126): 5.43e-54: 166: 98.41		MDC1_HUMAN (907-2156): 1.96e-13: 78.7: 10.22
+	Hs
		918364 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		MDC1_HUMAN (907-2156): 1.96e-13: 78.7: 10.22
+	Hs
		241615 H2B1K_HUMAN (1-126): 1.2e-53: 166: 100.00		CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78
+	Hs
		1274405 H2B1H_HUMAN (1-126): 5.43e-54: 166: 98.41		ZN469_HUMAN (1581-2152): 9.82e-09: 63.1: 11.51