HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: TRA2A (Q13595)
Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)
Gene: TRA2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 282
+	Hs
		241339 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		TRA2B_HUMAN (1-257): 9.05e-43: 149: 55.25
+	Hs
		240604 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		PABP1_HUMAN (1-267): 2.44e-37: 141: 14.13
+	Hs
		241583 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		PABP4_HUMAN (1-267): 1.76e-37: 141: 14.49
+	Hs
		241871 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		PAP1L_HUMAN (1-272): 3.52e-37: 140: 14.59
+	Hs
		242907 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		PABP3_HUMAN (1-267): 7.72e-34: 131: 13.77
+	Hs
		242395 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		PPIL4_HUMAN (117-195): 7.76e-27: 110: 39.24
+	Hs
		241422 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		TIAR_HUMAN (113-209): 9.71e-20: 89.4: 20.62
+	Hs
		240864 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		TIA1_HUMAN (114-207): 1.65e-18: 86.4: 21.28
+	Hs
		241643 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		CIRBP_HUMAN (121-193): 2.2e-10: 60.1: 58.90
+	Hs
		1102012 CUL9_HUMAN (30-463): 4.64e-78: 267: 18.81		PABP4_HUMAN (1-267): 1.76e-37: 141: 14.49
+	Hs
		1102083 HOIL1_HUMAN (12-448): 3.03e-67: 225: 16.36		PABP4_HUMAN (1-267): 1.76e-37: 141: 14.49
+	Hs
		550453 HOIL1_HUMAN (12-448): 3.03e-67: 225: 16.36		PABP1_HUMAN (1-267): 2.44e-37: 141: 14.13
+	Hs
		335083 ARI2_HUMAN (222-464): 9.66e-64: 215: 20.82		TRA2B_HUMAN (1-257): 9.05e-43: 149: 55.25
+	Hs
		334982 ARI2_HUMAN (222-464): 9.66e-64: 215: 20.82		PABP1_HUMAN (1-267): 2.44e-37: 141: 14.13
+	Hs
		335013 ARI2_HUMAN (222-464): 9.66e-64: 215: 20.82		TIA1_HUMAN (114-207): 1.65e-18: 86.4: 21.28
+	Hs
		335123 ARI2_HUMAN (222-464): 9.66e-64: 215: 20.82		CIRBP_HUMAN (121-193): 2.2e-10: 60.1: 58.90
+	At
		1041976 UBQ3_ARATH (1-77): 1.82e-30: 121: 31.17		RBG8_ARATH (122-195): 1.47e-27: 106: 40.54
+	At
		1050758 UBQ3_ARATH (1-77): 1.82e-30: 121: 31.17		PABP5_ARATH (117-251): 1.91e-18: 87.1: 23.91
+	At
		198413 UBQ3_ARATH (1-77): 1.82e-30: 121: 31.17		PABP4_ARATH (2-281): 2.1e-15: 77.9: 10.99