Interactor 1: DKC1 (O60832)
H/ACA ribonucleoprotein complex subunit DKC1 (EC 5.4.99.-) (CBF5 homolog) (Dyskerin) (Nopp140-associated protein of 57 kDa) (Nucleolar protein NAP57) (Nucleolar protein family A member 4) (snoRNP protein DKC1)
Gene: DKC1

Interactor 2: NAF1 (Q96HR8)
H/ACA ribonucleoprotein complex non-core subunit NAF1 (hNAF1)
Gene: NAF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.972

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 35271311, 19095616, 26496610, 16601202, 19179534
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Gar1~TruB_C_2, Gar1~TruB_N
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0032212 - positive regulation of telomere maintenance via telomerase
and 4 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 514
Hs

1 494
+ At
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024