HitPredict

Interactor 1: DNJA2 (O60884)
DnaJ homolog subfamily A member 2 (Cell cycle progression restoration gene 3 protein) (Dnj3) (Dj3) (HIRA-interacting protein 4) (Renal carcinoma antigen NY-REN-14)
Gene: DNAJA2

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008284 - positive regulation of cell population proliferation GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 412 Hs			1 768
+	Hs
		681439 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042259 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042743 DJB11_HUMAN (2-355): 1.66e-108: 325: 35.85		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		681440 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		681437 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		636327 DNJB1_HUMAN (10-356): 4.98e-50: 174: 36.49		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		681438 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		681547 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		CUL5_HUMAN (25-768): 0: 597: 23.77
+	Hs
		1274015 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		CUL5_HUMAN (25-768): 0: 597: 23.77
+	Zm
		26325 K7UU30_MAIZE (4-355): 3.55e-62: 206: 39.17		A0A1D6J2B8_MAIZE (17-768): 0: 709: 28.29