HitPredict

Interactor 1: ARI1 (Q94981)
E3 ubiquitin-protein ligase ariadne-1 (EC 2.3.2.31) (Protein ariadne-1) (RING-type E3 ubiquitin transferase ariadne-1)
Gene: ari-1

Interactor 2: ARI1 (Q94981)
E3 ubiquitin-protein ligase ariadne-1 (EC 2.3.2.31) (Protein ariadne-1) (RING-type E3 ubiquitin transferase ariadne-1)
Gene: ari-1

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.757

The method score is based on:

Property Details
Experiments 10880484, 29689197
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ariadne~IBR, Ariadne~IBR_1, Ariadne~zf-C3HC4, IBR~IBR, ARI1_UBAl~IBR, IBR~zf-C3HC4, IBR_1~IBR_1, zf-C3HC4~zf-C3HC4
Common GO terms GO:0000151 - ubiquitin ligase complex
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
and 9 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 503
Dm

1 503
+ Hs
+ Dm
+ At
+ Zm
+ Hs
+ Hs
+ Dm
+ Hs
+ At
+ Dm
+ Hs
+ Hs
+ Hs
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Last updated: 11Aug2025