HitPredict

Interactor 1: KIF5C (O60282)
Kinesin heavy chain isoform 5C (EC 3.6.4.-) (Kinesin heavy chain neuron-specific 2) (Kinesin-1)
Gene: KIF5C

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.687

Property	Details
Experiments	33961781, 35271311, 28514442, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 957 Hs			1 246
+	Hs
		913464 KIF11_HUMAN (8-866): 2.1e-162: 505: 27.69		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		971455 KIF5A_HUMAN (2-956): 2.25e-140: 447: 74.45		1433E_HUMAN (3-243): 4.41e-144: 405: 65.43
+	Hs
		729786 KIF5A_HUMAN (2-956): 2.25e-140: 447: 74.45		1433B_HUMAN (1-246): 3.49e-144: 404: 100.00
+	Mm
		749844 KIF5A_MOUSE (2-956): 7.06e-139: 443: 74.14		1433E_MOUSE (3-243): 4.41e-144: 405: 65.43
+	Hs
		990157 KIF5A_HUMAN (2-956): 2.25e-140: 447: 74.45		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		244146 KIF5C_HUMAN (1-957): 4.12e-130: 418: 100.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		913473 KIF11_HUMAN (8-866): 2.1e-162: 505: 27.69		1433F_HUMAN (4-244): 2.72e-107: 311: 75.51
+	Mm
		704810 KIF5C_MOUSE (1-957): 7.34e-129: 414: 97.81		1433Z_MOUSE (3-244): 3.15e-142: 399: 88.02
+	Hs
		690952 KIF5A_HUMAN (2-956): 2.25e-140: 447: 74.45		1433T_HUMAN (3-244): 3.25e-127: 361: 81.82
+	Hs
		972034 KI13B_HUMAN (6-762): 5.16e-114: 388: 23.49		1433E_HUMAN (3-243): 4.41e-144: 405: 65.43
+	Hs
		730274 KI13B_HUMAN (6-762): 5.16e-114: 388: 23.49		1433B_HUMAN (1-246): 3.49e-144: 404: 100.00
+	Hs
		990773 KI13B_HUMAN (6-762): 5.16e-114: 388: 23.49		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		244133 KIF5C_HUMAN (1-957): 4.12e-130: 418: 100.00		1433T_HUMAN (3-244): 3.25e-127: 361: 81.82
+	Hs
		966252 KIF5A_HUMAN (2-956): 2.25e-140: 447: 74.45		1433G_HUMAN (3-246): 1.92e-109: 317: 75.40
+	Hs
		1049241 KIF5A_HUMAN (2-956): 2.25e-140: 447: 74.45		1433F_HUMAN (4-244): 2.72e-107: 311: 75.51
+	Hs
		691462 KI13B_HUMAN (6-762): 5.16e-114: 388: 23.49		1433T_HUMAN (3-244): 3.25e-127: 361: 81.82
+	Hs
		244145 KIF5C_HUMAN (1-957): 4.12e-130: 418: 100.00		1433G_HUMAN (3-246): 1.92e-109: 317: 75.40
+	Hs
		244149 KIF5C_HUMAN (1-957): 4.12e-130: 418: 100.00		1433F_HUMAN (4-244): 2.72e-107: 311: 75.51
+	Hs
		966911 KI13B_HUMAN (6-762): 5.16e-114: 388: 23.49		1433G_HUMAN (3-246): 1.92e-109: 317: 75.40
+	Hs
		730907 KI13B_HUMAN (6-762): 5.16e-114: 388: 23.49		1433S_HUMAN (3-239): 3.4e-100: 293: 68.62