HitPredict

Interactor 1: SI1L3 (O60292)
Signal-induced proliferation-associated 1-like protein 3 (SIPA1-like protein 3) (SPA-1-like protein 3)
Gene: SIPA1L3

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.709

Property	Details
Experiments	33961781, 36931259, 24255178, 28514442, unassigned3799
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1781 Hs			1 246
+	Hs
		972088 SI1L2_HUMAN (1-1774): 0: 1333: 44.16		1433E_HUMAN (3-243): 4.41e-144: 405: 65.43
+	Hs
		730314 SI1L2_HUMAN (1-1774): 0: 1333: 44.16		1433B_HUMAN (1-246): 3.49e-144: 404: 100.00
+	Hs
		990820 SI1L2_HUMAN (1-1774): 0: 1333: 44.16		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		244561 SI1L3_HUMAN (1-1781): 0: 1320: 100.00		1433E_HUMAN (3-243): 4.41e-144: 405: 65.43
+	Hs
		244565 SI1L3_HUMAN (1-1781): 0: 1320: 100.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		691503 SI1L2_HUMAN (1-1774): 0: 1333: 44.16		1433T_HUMAN (3-244): 3.25e-127: 361: 81.82
+	Hs
		244536 SI1L3_HUMAN (1-1781): 0: 1320: 100.00		1433T_HUMAN (3-244): 3.25e-127: 361: 81.82
+	Hs
		966971 SI1L2_HUMAN (1-1774): 0: 1333: 44.16		1433G_HUMAN (3-246): 1.92e-109: 317: 75.40
+	Hs
		1049863 SI1L2_HUMAN (1-1774): 0: 1333: 44.16		1433F_HUMAN (4-244): 2.72e-107: 311: 75.51
+	Hs
		244559 SI1L3_HUMAN (1-1781): 0: 1320: 100.00		1433G_HUMAN (3-246): 1.92e-109: 317: 75.40
+	Hs
		244569 SI1L3_HUMAN (1-1781): 0: 1320: 100.00		1433F_HUMAN (4-244): 2.72e-107: 311: 75.51
+	Hs
		730935 SI1L2_HUMAN (1-1774): 0: 1333: 44.16		1433S_HUMAN (3-239): 3.4e-100: 293: 68.62
+	Hs
		244539 SI1L3_HUMAN (1-1781): 0: 1320: 100.00		1433S_HUMAN (3-239): 3.4e-100: 293: 68.62
+	Hs
		208648 SI1L1_HUMAN (3-1773): 0: 1091: 44.78		1433E_HUMAN (3-243): 4.41e-144: 405: 65.43
+	Hs
		208626 SI1L1_HUMAN (3-1773): 0: 1091: 44.78		1433B_HUMAN (1-246): 3.49e-144: 404: 100.00
+	Hs
		208650 SI1L1_HUMAN (3-1773): 0: 1091: 44.78		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		208622 SI1L1_HUMAN (3-1773): 0: 1091: 44.78		1433T_HUMAN (3-244): 3.25e-127: 361: 81.82
+	Hs
		208647 SI1L1_HUMAN (3-1773): 0: 1091: 44.78		1433G_HUMAN (3-246): 1.92e-109: 317: 75.40
+	Hs
		208655 SI1L1_HUMAN (3-1773): 0: 1091: 44.78		1433F_HUMAN (4-244): 2.72e-107: 311: 75.51
+	Hs
		208627 SI1L1_HUMAN (3-1773): 0: 1091: 44.78		1433S_HUMAN (3-239): 3.4e-100: 293: 68.62