HitPredict

Interactor 1: SI1L3 (O60292)
Signal-induced proliferation-associated 1-like protein 3 (SIPA1-like protein 3) (SPA-1-like protein 3)
Gene: SIPA1L3

Interactor 2: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	33961781, 35271311, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1781 Hs			1 255
+	Hs
		972088 SI1L2_HUMAN (1-1774): 0: 1333: 44.16		1433E_HUMAN (1-255): 4.89e-154: 430: 100.00
+	Hs
		208648 SI1L1_HUMAN (3-1773): 0: 1091: 44.78		1433E_HUMAN (1-255): 4.89e-154: 430: 100.00
+	Hs
		890804 TSC2_HUMAN (27-876): 0: 711: 16.13		1433E_HUMAN (1-255): 4.89e-154: 430: 100.00
+	Hs
		971644 RGPA1_HUMAN (288-850): 1.62e-121: 427: 18.83		1433E_HUMAN (1-255): 4.89e-154: 430: 100.00
+	Hs
		971635 RPGP2_HUMAN (377-891): 1.45e-123: 408: 30.04		1433E_HUMAN (1-255): 4.89e-154: 430: 100.00
+	Dm
		1019948 Q9VW83_DROME (319-834): 2.03e-115: 407: 17.39		1433E_DROME (1-254): 2.96e-146: 411: 82.69
+	Dm
		120292 M9PD17_DROME (319-834): 1.71e-115: 407: 17.39		1433E_DROME (1-254): 2.96e-146: 411: 82.69
+	Hs
		866518 RPGP1_HUMAN (415-842): 4.36e-111: 371: 32.24		1433E_HUMAN (1-255): 4.89e-154: 430: 100.00
+	Hs
		971813 DLG5_HUMAN (793-1750): 1.77e-60: 232: 10.54		1433E_HUMAN (1-255): 4.89e-154: 430: 100.00
+	Hs
		972155 MAST1_HUMAN (986-1525): 3.36e-33: 142: 14.34		1433E_HUMAN (1-255): 4.89e-154: 430: 100.00
+	Hs
		319058 K0754_HUMAN (1329-1772): 2.56e-27: 124: 12.42		1433E_HUMAN (1-255): 4.89e-154: 430: 100.00
+	Hs
		971678 OTOG_HUMAN (1038-1600): 2.12e-14: 81.6: 13.00		1433E_HUMAN (1-255): 4.89e-154: 430: 100.00
+	Hs
		971704 TICRR_HUMAN (1062-1665): 3.53e-09: 64.4: 12.38		1433E_HUMAN (1-255): 4.89e-154: 430: 100.00