HitPredict

Interactor 1: CCNT1 (O60563)
Cyclin-T1 (CycT1) (Cyclin-T)
Gene: CCNT1

Interactor 2: MAX (P61244)
Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X)
Gene: MAX

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17700062
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0140297 - DNA-binding transcription factor binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 726 Hs			1 160
+	Hs
		251493 CCNT1_HUMAN (1-715): 0: 591: 100.00		MYC_HUMAN (14-105): 1.82e-21: 91.5: 34.74
+	Mm
		704119 CCNT1_MOUSE (1-707): 0: 562: 89.25		MAX_MOUSE (1-160): 4.62e-32: 113: 99.38
+	Mm
		373710 CCNT1_MOUSE (1-707): 0: 562: 89.25		MYC_MOUSE (19-105): 1.04e-21: 91.9: 37.50
+	Hs
		573766 CCNB1_HUMAN (4-281): 4.02e-75: 250: 12.95		SRBP1_HUMAN (9-149): 2.93e-25: 102: 20.00
+	Hs
		296948 CCNK_HUMAN (12-335): 7.08e-71: 244: 25.38		MYC_HUMAN (14-105): 1.82e-21: 91.5: 34.74
+	Hs
		296954 CCNK_HUMAN (12-335): 7.08e-71: 244: 25.38		MYCL_HUMAN (7-104): 3.79e-20: 86.9: 30.77
+	Hs
		371518 CCNH_HUMAN (29-309): 3.78e-56: 196: 15.92		MYC_HUMAN (14-105): 1.82e-21: 91.5: 34.74