Protein: CCNH
Cyclin-H (MO15-associated protein) (p34) (p37)

Gene: CCNH
Organism: Homo sapiens
Interactions: 83
UniProt ID: P51946

Gene Ontology (top 5):
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0000439 - transcription factor TFIIH core complex
GO:0001673 - male germ cell nucleus
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

897171

CDK7
Cyclin-dependent kinase 7

26

20

Small-scale

0.992

High

667665

CDK2
Cyclin-dependent kinase 2

10

20

Small-scale

0.975

High

908691

CDK3
Cyclin-dependent kinase 3

2

20

High-throughput

0.783

High

908692

CDK6
Cyclin-dependent kinase 6

2

20

High-throughput

0.783

High

622781

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

10

4

Small-scale

0.749

High

908687

MAT1
CDK-activating kinase assembly factor MAT1

8

7

Small-scale

0.748

High

908706

CDK20
Cyclin-dependent kinase 20

1

20

Small-scale

0.713

High

680817

PSA1
Proteasome subunit alpha type-1

4

2

High-throughput

0.705

High

611657

ERCC2
General transcription and DNA repair factor IIH helicase subunit XPD

4

2

Small-scale

0.694

High

666815

CCNC
Cyclin-C

1

10

Small-scale

0.692

High

881495

CDK8
Cyclin-dependent kinase 8

1

20

Small-scale

0.692

High

132454

CDC7
Cell division cycle 7-related protein kinase

1

20

High-throughput

0.691

High

573780

CCNB1
G2/mitotic-specific cyclin-B1

1

6

High-throughput

0.691

High

744643

TF2H1
General transcription factor IIH subunit 1

5

1

Small-scale

0.691

High

908724

DUS12
Dual specificity protein phosphatase 12

4

0

High-throughput

0.668

High

704730

ERCC5
DNA excision repair protein ERCC-5

3

7

High-throughput

0.667

High

908695

GOGA2
Golgin subfamily A member 2

5

2

High-throughput

0.657

High

908725

MTMR7
Phosphatidylinositol-3-phosphate phosphatase MTMR7

5

1

High-throughput

0.649

High

395725

ESR1
Estrogen receptor

3

19

Small-scale

0.633

High

908699

TF2H2
General transcription factor IIH subunit 2

3

1

Small-scale

0.633

High

730459

1433S
14-3-3 protein sigma

2

4

High-throughput

0.628

High

908696

LIPA1
Liprin-alpha-1

3

1

High-throughput

0.617

High

66971

CPS4L
Putative cleavage and polyadenylation specificity factor subunit 4-like protein

3

1

High-throughput

0.609

High

908711

TBC15
TBC1 domain family member 15

3

2

High-throughput

0.609

High

250225

VINEX
Vinexin

2

5

High-throughput

0.606

High

587031

ITF2
Transcription factor 4

2

1

High-throughput

0.606

High

899305

TCPD
T-complex protein 1 subunit delta

2

3

High-throughput

0.606

High

908702

GRAP1
GRIP1-associated protein 1

2

2

High-throughput

0.606

High

908726

ADIP
Afadin- and alpha-actinin-binding protein

2

0

High-throughput

0.606

High

667223

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

5

Small-scale

0.602

High

371518

MYC
Myc proto-oncogene protein

2

7

Small-scale

0.595

High

908708

ZN655
Zinc finger protein 655

2

0

High-throughput

0.580

High

908715

MCRS1
Microspherule protein 1

2

0

High-throughput

0.580

High

908720

GO45
Golgin-45

2

0

High-throughput

0.580

High

908703

KLC3
Kinesin light chain 3

2

3

High-throughput

0.573

High

163911

NDC80
Kinetochore protein NDC80 homolog

1

3

High-throughput

0.573

High

908697

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

3

High-throughput

0.573

High

908688

CTBP2
C-terminal-binding protein 2

1

0

High-throughput

0.567

High

413450

P53
Cellular tumor antigen p53

1

9

Small-scale

0.561

High

519862

ANDR
Androgen receptor

1

19

Small-scale

0.561

High

520537

RARA
Retinoic acid receptor alpha

1

15

Small-scale

0.561

High

861528

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

3

Small-scale

0.561

High

908701

RHOH
Rho-related GTP-binding protein RhoH

2

1

High-throughput

0.553

High

908709

TRIMM
Probable E3 ubiquitin-protein ligase TRIML2

2

3

High-throughput

0.553

High

533219

RARB
Retinoic acid receptor beta

1

15

High-throughput

0.541

High

908689

CSK2B
Casein kinase II subunit beta

1

3

High-throughput

0.541

High

256601

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

1

High-throughput

0.536

High

273839

CNOT3
CCR4-NOT transcription complex subunit 3

1

3

High-throughput

0.536

High

574045

HXB1
Homeobox protein Hox-B1

1

5

High-throughput

0.536

High

908705

CC170
Coiled-coil domain-containing protein 170

1

2

High-throughput

0.523

High

908717

HTF4
Transcription factor 12

1

1

High-throughput

0.515

High

261481

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.513

High

832881

CETN2
Centrin-2

1

0

High-throughput

0.513

High

908704

TF2H5
General transcription factor IIH subunit 5

1

0

High-throughput

0.513

High

908719

BC11B
B-cell lymphoma/leukemia 11B

1

0

High-throughput

0.513

High

130406

SPT5H
Transcription elongation factor SPT5

1

4

Small-scale

0.501

High

722915

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

1

Small-scale

0.501

High

908712

TF2H4
General transcription factor IIH subunit 4

1

1

Small-scale

0.500

High

908700

GANAB
Neutral alpha-glucosidase AB

1

1

High-throughput

0.494

High

322494

ABLM3
Actin-binding LIM protein 3

1

2

High-throughput

0.489

High

908694

LMNB2
Lamin-B2

1

3

High-throughput

0.489

High

908718

TRIM8
E3 ubiquitin-protein ligase TRIM8

1

5

High-throughput

0.481

High

259655

BRD4
Bromodomain-containing protein 4

1

15

High-throughput

0.479

High

573396

ENPL
Endoplasmin

1

3

High-throughput

0.479

High

588254

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.479

High

694979

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

756132

MCM7
DNA replication licensing factor MCM7

1

5

Small-scale

0.479

High

767748

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.479

High

798870

BRCA1
Breast cancer type 1 susceptibility protein

1

5

Small-scale

0.479

High

908698

MTA1
Metastasis-associated protein MTA1

1

1

Small-scale

0.479

High

908713

FUBP1
Far upstream element-binding protein 1

1

1

Small-scale

0.479

High

908722

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

908723

XPO7
Exportin-7

1

6

High-throughput

0.479

High

908716

RADIL
Ras-associating and dilute domain-containing protein

1

2

High-throughput

0.470

High

908714

DDT4L
DNA damage-inducible transcript 4-like protein

1

1

High-throughput

0.470

High

908690

ACTC
Actin, alpha cardiac muscle 1

1

2

High-throughput

0.437

High

908693

XPC
DNA repair protein complementing XP-C cells

1

0

Small-scale

0.426

High

239028

ZNRD2
Protein ZNRD2

3

0

High-throughput

0.354

High

908721

PICK1
PRKCA-binding protein

2

0

High-throughput

0.316

High

224474

PI15
Peptidase inhibitor 15

1

0

High-throughput

0.279

Low

908710

IL17D
Interleukin-17D

1

0

High-throughput

0.279

Low

333312

SNAPN
SNARE-associated protein Snapin

1

0

High-throughput

0.268

Low

908707

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025