HitPredict

Interactor 1: CG1C (O74627)
Cyclin pch1 (Pombe cyclin C homolog 1)
Gene: pch1

Interactor 2: CDK9 (Q96WV9)
Probable cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 9)
Gene: CDK9

Species: Schizosaccharomyces pombe 972h-

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.885

The method score is based on:

Property Details
Experiments 12475973, 16428435, 29899453, 17332744
Identification Methods two hybrid, affinity chromatography technology, enzymatic study, tandem affinity purification
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0005634 - nucleus
GO:0070691 - P-TEFb complex
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 342
Sp

1 591
+ At
+ At
+ At
+ At
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm
+ Mm
+ Mm
+ At
+ Hs
+ At
+ Hs
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024