HitPredict

Interactor 1: KLH41 (O60662)
Kelch-like protein 41 (Kel-like protein 23) (Kelch repeat and BTB domain-containing protein 10) (Kelch-related protein 1) (Sarcosin)
Gene: KLHL41

Interactor 2: KLH40 (Q2TBA0)
Kelch-like protein 40 (Kelch repeat and BTB domain-containing protein 5) (Sarcosynapsin)
Gene: KLHL40

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains BACK~BTB, BTB~BTB
Common GO terms GO:0005737 - cytoplasm
GO:0031463 - Cul3-RING ubiquitin ligase complex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
GO:1990756 - ubiquitin-like ligase-substrate adaptor activity
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 606
Hs

1 621
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Service provided by Combinatics, Japan

Last updated: 11Aug2025